外耳道内推注曲安奈德益康唑乳膏治疗真菌性外耳道炎的疗效观察  

Therapeutic effect of triamcinolone acetonide and econazole cream in the treatment of fungal otitis externa

作　　者：李妍 王昭迪[1] 臧志敏 高宁 孙书连 安庆华[1] Li Yan;Wang Zhaodi;Zang Zhimin;Gao Ning;Sun Shulian;An Qinghua(Otolaryngology Head and Neck Surgery,Beijing Jingmei Group General Hospital,Beijing,102300,China)

机构地区：[1]北京京煤集团总医院,北京102300

出　　处：《中国医学文摘（耳鼻咽喉科学）》2023年第3期79-82,F0002,共5页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：目的探讨外耳道内推注曲安奈德益康唑乳膏治疗真菌性外耳道炎的临床效果。方法选取2021.6.1-2022.6.1我院耳鼻喉科收治的92例(92耳)真菌性外耳道炎患者,根据治疗方法的不同分为对照组和病例组,各46例。所有患者首先于耳内镜下清洁外耳道,对照组嘱患者回家后自行涂药2次/日,14天后复查。病例组由医师向外耳道内推注曲安奈德益康唑乳膏并吸除多余膏体,每3天复诊1次,共治疗5次。比较两组的临床疗效、不良反应。随访3个月,比较两组复发率。结果对照组总有效率38/46(82.61%),病例组总有效率44/46(95.65%),病例组总有效率高于对照组,P=0.044(小于0.05),差异有统计学意义。结论向外耳道内推注曲安奈德益康唑乳膏治疗真菌性外耳道炎疗效确切、操作简单,值得临床推广。Objective To investigate the clinical effect of triamcinolone acetonide and econazole cream in the treatment of fungal otitis externa.Methods 92 patients(92 ears)with fungal external otitis were selected from the department of otolaryngology of our hospital from January 2021.6.1 to January 2022.6.1.They were divided into control group and case group according to different treatment methods,with 46 cases each.All patientsfirst cleaned the external auditory canal under the ear endoscope,and the control group instructed the patients to apply medicine twice a day after returning home,and then rechecked 14 days later.In the case group,the physician injected triamcinolone acetonide and econazole cream into the external ear canal and sucked off the excess cream.The patient was revisited once every 3 days,with a total of 5 times of treatment.The clinical efficacy and adverse reactions of the two groups were compared.Follow up for 3 months and compare the recurrence rate of the two groups.Results The total effective rate of the control group was 38/46(82.61%),and the total effective rate of the case group was 44/46(95.65%).The total effective rate of the case group was higher than that of the control group,P=0.044(less than 0.05),and the difference was statistically significant.Conclusion Injecting triamcinolone acetonide and econazole cream into the external auditory canal in the treatment of fungal otitis externa has definite curative effect and simple operation,which is worthy of clinical promotion.

关 键 词：真菌性外耳道炎 曲安奈德益康唑乳膏 曲霉菌 真菌 

分 类 号：R76[医药卫生—耳鼻咽喉科]