运脾补血汤辅助治疗小儿营养性缺铁性贫血脾胃虚弱证35例临床观察  

Clinical observation on 35 cases of Yunpi Buxue Tang(运脾补血汤)in adjuvant treatment of pediatric nutritional iron deficiency anemia with spleen and stomach weakness syndrome

作　　者：张银敏[1] 徐浩岑[1] 钱雄[1] ZHANG Yinmin;XU Haocen;QIANG Xiong(Department of Pediatrics,Jiaxing Hospital of Traditional Chinese Medicine,Jiaxing,Zhejiang,314001,China)

机构地区：[1]嘉兴市中医医院儿科,浙江嘉兴314001

出　　处：《中医儿科杂志》2023年第3期45-49,共5页Journal of Pediatrics of Traditional Chinese Medicine

基　　金：浙江省中医药科技计划项目(2020ZB254)。

摘　　要：目的 观察运脾补血汤辅助治疗小儿营养性缺铁性贫血脾胃虚弱证的临床疗效。方法 选取2020年4—9月嘉兴市中医医院儿科收治的小儿营养性缺铁性贫血脾胃虚弱证患儿70例,按照随机数字表法分为对照组和治疗组,各35例。对照组予葡萄糖酸亚铁糖浆口服,治疗组在对照组治疗方法的基础上予中药运脾补血汤治疗,2组均连续治疗4周后统计临床疗效。结果 对照组总有效率为77.14%(27/35),治疗组为97.14%(34/35),2组总有效率比较,差异有统计学意义(P<0.05)。治疗前,2组血清血红蛋白(Hb)、红细胞平均血红蛋白量(MCH)、红细胞平均体积(MCV)、红细胞平均血红蛋白浓度(MCHC)水平比较,差异均无统计学意义(P>0.05),具有可比性;治疗后,2组的上述指标水平均明显升高,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组升高更显著(P<0.05)。治疗前,2组血清铁(SI)、铁蛋白(SF)、转铁蛋白(TRF)水平比较,差异均无统计学意义(P>0.05),具有可比性;治疗后,2组血清SI、SF水平均明显升高,TRF水平明显下降,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组升高或下降更显著(P<0.05)。治疗前,2组面色、纳食、精神和腹胀便溏积分以及总积分比较,差异均无统计学意义(P>0.05),具有可比性;治疗后,2组上述积分均明显下降,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组下降更显著(P<0.05)。2组治疗过程中均未发生肝肾功能损害,对照组不良反应总发生率为17.14%(6/35),治疗组为11.43%(4/35),2组比较,差异无统计学意义(P>0.05)。结论 运脾补血汤辅助治疗小儿营养性缺铁性贫血脾胃虚弱证,疗效确切,不仅能明显改善患儿的临床症状、贫血相关指标及铁代谢水平,而且无明显不良反应,值得临床推广应用。Objective To observe the clinical efficacy of Yunpi Buxue Tang(运脾补血汤)in adjuvant treatment of pediatric nutritional iron deficiency anemia.Methods 70 cases of pediatric nutritional iron deficiency anemia treated in the Pediatric Department of Jiaxing Traditional Chinese Medicine Hospital from April 2020 to September 2020 were selected and divided into a control group(n=35)and a treatment group(n=35)using a random number table.The control group was given conventional treatment with Western medicine,while the treatment group was given Yunpi Buxue Tang on the basis of conventional treatment.The clinical efficacy was compared between the two groups after 4 weeks of continuous treatment.Results The total effective rate was 77.14%(27/35)in the control group and 97.14%(34/35)in the treatment group,with a statistically significant difference between the two groups(P<0.05).Before treatment,there was no significant difference in the levels of serum hemoglobin(Hb),mean corpuscular hemoglobin(MCH),mean corpuscular volume(MCV),and mean corpuscular hemoglobin concentration(MCHC)between the two groups(P>0.05),indicating comparability.After treatment,the levels of these indicators in both groups were significantly increased compared with before treatment,and the increase was more significant in the treatment group(P<0.05).Before treatment,there was no significant difference in the levels of serum iron(SI),ferritin(SF),and transferrin(TRF)between the two groups(P>0.05),indicating comparability.After treatment,the levels of SI and SF in both groups were significantly increased,while the level of TRF was significantly decreased compared with before treatment,and the increase or decrease was more significant in the treatment group(P<0.05).Before treatment,there was no significant difference in the scores of facial complexion,appetite,spirit,abdominal distension,diarrhea,and total score between the two groups(P>0.05),indicating comparability.After treatment,the scores of these indicators in both groups were significantly de

关 键 词：营养性缺铁性贫血 小儿 脾胃虚弱证 运脾补血汤 临床观察 

分 类 号：R556.3[医药卫生—血液循环系统疾病]