基于磁共振扩散张量成像探讨ADC值及FA值与椎体压缩性骨折时间的相关性  

Study on The Correlation Between ADC Value and FA Value and Vertebral Compression

作　　者：徐安琪 原子扬 贺顺岭 王存强 顾韵泽 XU An-qi;YUAN Zi-yang;HE Shun-ling;WANG Cun-qiang;GU Yun-ze(Magnetic resonance Department,Xinxiang Medical University,the Fifth Clinical College,Xinxiang 453099,Henan Province,China)

机构地区：[1]新乡医学院第五临床学院磁共振科,河南新乡453100

出　　处：《中国CT和MRI杂志》2023年第6期156-158,共3页Chinese Journal of CT and MRI

基　　金：河南省科技攻关基金资助项目(182102310480)。

摘　　要：目的通过MRI表现与椎体压缩骨折外伤时间的相关性研究,寻找椎体损伤后骨折区及水肿区恢复变化规律,探讨MRI表观扩散系数(ADC值)及各向异性分数(FA值)在推断外伤性椎体压缩骨折时间中的应用价值。方法选取55~65岁女性明确外伤时间患者3例。根据受伤时间分为8个时段,连续进行磁共振动态扫描检查,脊柱线圈TSE序列,常规行矢状位T_(1)WI、T_(2)WI、T_(2)WI-FS扫描,轴位T_(2)WI、DTI扫描,监测观察受伤椎体骨折线区、水肿区及相邻正常椎体的ADC值及FA值。结果:骨折线区在椎体压缩骨折发生后10~30天时,与骨折发生后60~90天时ADC值有明显差异(P<0.05);在骨折发生后0~30天时,与骨折发生后60~90天时FA值有明显差异(P<0.05);椎体受伤后150天内,骨折线区ADC值及FA值与正常区相比,均有明显差异(P<0.05)。骨折发生时骨折线区ADC呈高信号,随着时间增加,骨折线区ADC值呈缓慢下降趋势,但整体数值高于正常区;骨折发生后骨折线区FA值随时间持续缓慢上升,但总体低于正常区FA值。水肿区在骨折50天内与骨折90天后ADC值具有明显差异(P<0.05);骨折40天内与骨折90天后FA值具有明显差异(P<0.05);骨折超过90天后,水肿区ADC值及FA值均与正常区无明显差异(P>0.05)。水肿区的ADC值缓慢上升约1月后持续下降,最终趋于正常;FA值随骨折愈合过程的进展持续升高,逐渐与正常区FA值接近。结论:利用弥散张量成像技术指标ADC值和各项异性指数FA值,可以为推测椎体损伤时间提供重要依据,为椎体判断受损时间以及评价治疗效果提供新方法。Objective Through the study on the correlation between the trauma time of vertebral compression fracture and MRI performance,to find the change law of edema recovery after vertebral injury,and the application value of MRI apparent diffusion coefficient(ADC)and fractional anisotropy(FA)in inferring the time of traumatic vertebral compression fracture was discussed.Methods Three female patients aged 55-65 with definite trauma time were selected.According to the injury time,they were divided into 8 periods.Continuous and dynamic magnetic resonance scanning,spinal coil TSE sequence,sagittal T_(1)WI scanning,T_(2)WI scanning,T_(2)WI-FS scanning,axial T_(2)WI scanning and DTI scanning were performed.FA and ADC values of fracture line area,edema area and adjacent normal vertebral bodies were monitored and observed.Results There was significant difference in ADC value between 10~30 days after vertebral compression fracture and 60~90 days after fracture(P<0.05);There was significant difference in FA value between 0~30 days after fracture and 60~90 days after fracture(P<0.05);Within 150 days after vertebral body injury,ADC and FA values in fracture line area were significantly different from those in normal area(P<0.05).The ADC in fracture line area showed high signal when fracture occurred.With the increase of time,the ADC value in fracture line area showed a slow downward trend,but the overall value was higher than that in normal area;After fracture,the FA value of fracture line area continued to rise slowly with time,but it was generally lower than that of normal area.There was significant difference in ADC value between edema area within 50 days and 90 days after fracture(P<0.05);There was significant difference in FA value between 40 days after fracture and 90 days after fracture(P<0.05);After more than 90 days of fracture,there was no significant difference in ADC value and FA value between edema area and normal area(P>0.05).The ADC value of edema area increased slowly,decreased continuously after about 1 month,and f

关 键 词：腰椎 压缩性骨折 磁共振扩散张量成像 表观扩散系数 各向异性分数 

分 类 号：R683[医药卫生—骨科学] R445.2[医药卫生—外科学]