基于多参数MRI的影像组学在子宫内膜癌淋巴血管间隙侵犯中的研究进展  

Research progress of radiomics based on multi-parameter MRI in lymphatic space invasion of endometrial cancer

作　　者：赵纪福 曹新山[1] ZHAO Jifu;CAO Xinshan(Department of Radiology,Affiliated Hospital of Binzhou Medical College,Binzhou 256603,China)

机构地区：[1]滨州医学院附属医院放射科,滨州256603

出　　处：《磁共振成像》2023年第6期171-175,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：山东省科技发展计划项目(编号:2010GSF10265)。

摘　　要：在影响子宫内膜癌(endometrial carcinoma, EC)预后的众多因素中,淋巴血管间隙侵犯(lymph vascular space invasion, LVSI)是一个重要的独立危险因素且目前常规影像学方法不能在术前对其进行准确诊断。近年来,多参数磁共振成像(multi-parameter magnetic resonance imaging, mpMRI)的影像组学对诊断EC的LVSI表现出巨大的潜力,使术前准确诊断LVSI成为可能,本综述对mpMRI影像组学在EC LVSI中的最新研究进展进行了总结及比较,并创新性地提出了将mpMRI的影像组学与肿瘤标志物人附睾蛋白4(human epididymis protein 4, HE4)结合构建组学模型,旨在提高LVSI的检出率,对患者的病情进展进行更加准确的判断,从而辅助临床对患者进行更加精准的治疗,提高患者的预后。Among the numerous factors that affect the prognosis of endometrial cancer(EC),lymphatic vascular space invasion(LVSI)is an important independent risk factor,and current conventional imaging methods cannot accurately diagnose it before surgery.In recent years,the radioomics of multi-parameter magnetic resonance imaging(mpMRI)has shown great potential for diagnosing LVSI in EC,making it possible to accurately diagnose LVSI before surgery.This review summarizes and compares the latest research progress of mpMRI radiomics in EC LVSI,and innovatively proposed combining the radiomics of mpMRI with the tumor marker HE4(human epididymis protein 4)to construct the radiomics model,aiming to improve the detection rate of LVSI and make more accurate judgments of patient progression,thereby assisting clinical treatment of patients with more precise treatment and improving their prognosis.

关 键 词：子宫内膜癌 淋巴血管间隙侵犯 术前预测 多参数 磁共振成像 影像组学 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.33[医药卫生—诊断学]