针灸联合补阳还五汤治疗恢复期中风气虚血瘀证临床研究  

Clinical Study on Acupuncture and Moxibustion Combined with Yang-Supplementing and Five-Returning Decoction in Treating Stroke with Qi Deficiency and Blood Stasis Syndrome in the Recovery Stage

作　　者：曲彦平 QU Yan-ping(Jiyuan Hospital of Traditional Chinese Medicine,Jiyuan,Henan,China,459000)

机构地区：[1]济源市中医院,河南济源459000

出　　处：《河南中医》2023年第6期923-927,共5页Henan Traditional Chinese Medicine

基　　金：河南省医学科技攻关项目(201702603)。

摘　　要：目的:观察针灸联合补阳还五汤治疗恢复期中风气虚血瘀证的临床疗效。方法:将102例恢复期中风气虚血瘀证患者按照随机数字表法分为对照组和研究组,每组各51例。两组患者入院后均给予常规治疗,对照组给予补阳还五汤治疗,研究组在对照组治疗的基础上联合针灸治疗。比较两组患者的临床疗效及治疗前后神经因子水平[神经营养因子(nerve trophic factor,NTF)、神经元异性烯醇化酶(neuron specific enolase,NSE)、神经生长因子(nerve growth factor,NGF)]、生活能力评分情况[Barthel指数(Barthel index,BI)评分、Fugl-meyer评分量表(Fugl-meyer assessment,FMA)评分、改良的Ashworth评分量表(modified ashworth scale,MAS)评分]、神经功能缺损情况、中医证候积分、血脂水平[同型半胱氨酸(homocysteine,Hcy)、总胆固醇(total cholesterol,TC)、三酰甘油(triacylglycerol,TG)、低密度脂蛋白(low density lipoprotein cholesterol,LDL-C)和高密度脂蛋白(high density lipoprotein cholesterol,HDL-C)]变化情况。结果:两组患者治疗后NTF、NGF、HDL-C高于本组治疗前,NSE、Hcy、TC、LDL-C、TG低于本组治疗前,且治疗后组间比较,差异具有统计学意义(P<0.05)。两组患者治疗后BI、FMA、MAS评分高于本组治疗前,且治疗后研究组高于对照组(P<0.05)。两组患者治疗后言语謇涩、意识不清、肢体偏瘫、口眼歪斜、NIHSS评分低于本组治疗前,且治疗后研究组低于对照组(P<0.05)。研究组有效率高于对照组(P<0.05)。结论:针灸联合补阳还五汤治疗恢复期中风气虚血瘀证,可有效改善患者的神经因子水平,促进神经功能恢复,同时还可提高患者的肢体运动功能、肌力情况及生活能力。Objective:To observe the clinical efficacy of acupuncture and moxibustion combined with Yang-Supplementing and Five-Returning Decoction on stroke with qi deficiency and blood stasis syndrome in the recovery stage.Methods:A total of 102 stroke patients with qi deficiency and blood stasis syndrome in the recovery period were randomly divided into the control group and the study group,with 51 cases in each group.Both groups were first given routine treatment after admission.Then the control group was treated with Yang-Supplementing and Five-Returning Decoction,while the study group was treated with acupuncture and moxibustion on the basis of the treatment in the control group.The clinical efficacy,the changes of the levels of nerve factors[including neurotrophin(NTF),neuron specific enolase(NSE),nerve growth factor(NGF)],the scores of ability to live[including Barthel index(BI)score,Fugl meyer assessment(FMA)score,modified Ashworth scale(MAS)score],neurological impairment,TCM syndrome scores,and blood lipid levels[including homocysteine(Hcy),total cholesterol(TC),triacylglycerol(TG),low density lipoprotein cholesterol(LDL-C)and high-density lipoprotein(HDL-C)]of the two groups before and after treatment were compared.Results:After treatment,the NTF,NGF,and HDL-C of the two groups were higher than those before treatment,while the NSE,Hcy,TC,LDL-C,and TG were lower than those before treatment,and all the differences between the two groups were statistically significant(P<0.05);The BI,FMA,and MAS scores of the two groups were higher than those before treatment,and the study group′s above indexes were higher than those of the control group after treatment(P<0.05);The two groups′patients had difficulty speaking,unclear consciousness,limb hemiplegia,mouth eye deviation,and NIHSS scores lower than those before treatment,and the study group′s above indexes were lower than those of the control group(P<0.05).The effective rate of the research group was higher than that of the control group(P<0.05).Conclusion::Acupunctur

关 键 词：中风 气虚血瘀证 补阳还五汤 针灸疗法 

分 类 号：R255.2[医药卫生—中医内科学]