补肾祛瘀汤对Ⅲ型前列腺炎合并前列腺增生症患者术后康复进程的影 响  

Effect of tonifying kidney and removing blood stasis decoction on postoperative rehabilitation process of patients with type III prostatitis complicated by prostate hyperplasia

作　　者：龚永明 潘世杰 Gong Yongming;Pan Shijie(Henan Hospital of Traditional Chinese Medicine,the Second Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450000,Henan,China)

机构地区：[1]河南省中医院(河南中医药大学第二附属医院),河南郑州450000

出　　处：《临床心身疾病杂志》2023年第3期103-108,共6页Journal of Clinical Psychosomatic Diseases

摘　　要：目的探讨补肾祛瘀汤对Ⅲ型前列腺炎合并前列腺增生症手术患者康复进程的影响。方法将90例Ⅲ型前列腺炎合并前列腺增生症患者随机分为观察组和对照组,各45例。两组均拟行前列腺汽化电切术治疗,对照组术后常规预防用药,观察组在对照组基础上术后3 d起加用补肾祛瘀汤治疗。对比两组术前、术后8周国际前列腺症状评分表评分、前列腺炎评分表评分、良性前列腺增生症生活质量量表评分、血清炎性因子(白细胞介素-6、白细胞介素-8、肿瘤坏死因子-α、巨噬细胞集落刺激因子)、病情相关指标(总前列腺特异性抗原、环氧合酶-2)、尿动力学指标(最大膀胱容量、最大尿流率、最大逼尿肌压力、最大尿道压)。结果术后8周观察组国际前列腺症状评分表、前列腺炎评分表评分低于对照组,最大逼尿肌压力、最大尿道压均低于对照组,最大膀胱容量、最大尿流率及良性前列腺增生症生活质量量表评分均高于对照组,差异有统计学意义(P<0.01);术后8周观察组白细胞介素-6、白细胞介素-8、肿瘤坏死因子-α、巨噬细胞集落刺激因子、总前列腺特异性抗原、环氧合酶-2水平低于对照组,差异有统计学意义(P<0.01或0.05)。结论补肾祛瘀汤应用于Ⅲ型前列腺炎合并前列腺增生症患者术后辅助治疗,能进一步减轻机体炎症状态,改善患者尿动力学,促进患者恢复。Objective To explore the effect of tonifying kidney and removing blood stasis decoction(TKRBSD)on postoperative rehabilitation process of patients with type III prostatitis(T3P)complicated by benign prostate hyperplasia(BPH).Methods Ninety T3P patients complicated by the BPH were randomly divided into observation(n=45)and control(n=45)group.Both groups were intended to undergo prostate vaporization electrotomy,after operation control group received routine prophylactic medication,and the observation was plus the TKRBSD from postoperative 3rd day on the basis of control group.Such indexes were compared as scores on the International Prostate Symptom Scale(IPSS),National Institutes of Health Chronic Prostatitis Symptom Index(NIH-CPSI),Benign Prostate Hyperplasia Quality of Life Scale(BPHQLS),and serum inflammatory factors,disease-related indexes,urodynamic indexes between two groups before operation and in postoperative 8 weeks.Results In postoperative 8 weeks scores on the IPSS and NIH-CPSI as well as maximum detrusor and maximum urethral pressure were lower in observation than in control group,maximum bladder capacity,maximum urine flow rate and score on the BPHQLS higher,and differences were statistically significant(P<0.01);in postoperative 8 weeks interleukin-6,interleukin-8,tumor necrosis factor-α,macrophage colony-stimulating factor,total prostate specific antigen and cyclooxygenase-2 levels were lower in observation than in control group,differences were statistically significant(P<0.01 or 0.05).Conclusion The TKRBSD as a postoperative adjuvant treatment for T3P patients complicated by the BPH could further reduce the organic inflammatory state,improve urodynamics,and promote rehabilitation process.

关 键 词：前列腺炎 前列腺增生 手术 补肾祛瘀汤 康复进程 

分 类 号：R697.3[医药卫生—泌尿科学]