2010-2020年山东省淄博市甲状腺癌发病特征与趋势分析  

Analysis of Thyroid Carcinoma Incidence Characteristics and Trends in Zibo City,Shandong Province from 2010 to 2020

作　　者：刘靖靖[1] 杨淑霞[1] 韩鹏 赵炫 李广益[1] 李琳琳 宋代琴[1] LIU Jingjing;YANG Shuxia;HAN Peng;ZHAO Xuan;LI Guangyi;LI Linlin;SONG Daiqin(Institute of Endemic and Chronic Disease Prevention and Control,Zibo Disease Prevention and Control Center,Zibo,Shandong Province,255026 China)

机构地区：[1]淄博市疾病预防控制中心地方病慢性病防制所,山东淄博255026

出　　处：《中国卫生产业》2023年第4期221-226,共6页China Health Industry

摘　　要：目的描述分析2010—2020年山东省淄博市甲状腺癌发病趋势,为制定淄博市甲状腺癌预防工作提供参考。方法收集2010—2020年淄博市肿瘤登记系统中户籍居民的肿瘤病例资料,计算甲状腺癌发病率、标化发病率,采用Joinpoint Regression Program 4.2软件计算年度变化百分比(annual percentage change,APC),以2010年全国第6次人口普查资料为标准计算标化率。结果2010—2020年淄博市甲状腺癌粗发病率为12.80/10万,标化发病率为11.85/10万;女性发病率是男性的3.47倍(P<0.05);甲状腺癌发病率40岁以上组达到最高峰(24.50/10万),之后发病率逐渐下降,各年龄组甲状腺癌发病率均为女性高于男性。2010—2014年淄博甲状腺癌发病率增长迅速,标化发病率APC值为136.52%(P<0.05);2014—2017年增长缓慢,标化发病率APC值为15.59%(P>0.05);2017—2020年持续增长,标化发病率APC值为28.81%(P<0.05)。各区县甲状腺癌发病率依据地理位置呈现中间高南北低的趋势,张店区和桓台县为甲状腺癌高发区,最高地区的标化发病率(201.03/10万)是最低地区(56.70/10万)的3.55倍。结论淄博市甲状腺癌发病率呈上升趋势,女性发病率均高于男性,40岁以上为甲状腺癌发病高峰,提示中年女性应作为甲状腺癌重点预防人群。Objective To describe and analyze the trend of thyroid carcinoma incidence in Zibo City,Shandong Province from 2010 to 2020,and to provide reference for the formulation of thyroid carcinoma prevention in Zibo City.Methods Information on tumor cases of household residents in the tumor registry system of Zibo from 2010 to 2020 was collected,and the incidence rate and standardized incidence rate of thyroid carcinoma were calculated.The annual percentage change(APC)was calculated using Joinpoint Regression Program 4.2 software,and the standardized incidence rate was calculated using the sixth national population census data in 2010.Results From 2010 to 2020,the crude incidence rate of thyroid carcinoma in Zibo was 12.80/100000 and the standardized incidence rate was 11.85/100000,with the incidence rate of women being 3.47 times higher than that of men(P<0.05);the incidence of thyroid cancer peaked in the 40 to age group(24.50/100000),after which the incidence gradually decreased,and the incidence of thyroid cancer in all age groups was higher in females than in males.From 2010 to 2014 thyroid carcinoma incidence in Zibo grew rapidly,with a standardized incidence APC value of 136.52%(P<0.05);the growth was slow from 2014 to 2017 with a standardized incidence APC value of 15.59%(P>0.05);the growth continued from 2017 to 2020 with a standardized incidence APC value of 28.81%(P<0.05).The incidence rate of thyroid carcinoma in each district and county showed a trend of high in the middle and low in the north and south based on geographical location.Zhangdian district and Huantai county were the high incidence areas of thyroid carcinoma,and the standardized incidence rate in the highest area(201.03/100000)was 3.55 times higher than that in the lowest area(56.70/100000)(P<0.05).Conclusion The incidence of thyroid carcinoma in Zibo city is on the rise,and the incidence rate of women is higher than that of men in all cases.The peak incidence of thyroid carcinoma is from 40 to age,suggesting that middle-aged women should be th

关 键 词：甲状腺癌 发病率 年度变化百分比 

分 类 号：R19[医药卫生—卫生事业管理]