Force-Triggered Guest Release from Mechanophore Incorporated Rotaxanes  

作　　者：Jinghui Yang Yan Xia 

机构地区：[1]Department of Chemistry,Stanford University,Stanford,California 94305

出　　处：《CCS Chemistry》2023年第6期1365-1371,共7页中国化学会会刊（英文）

基　　金：This work was supported by the U.S.Army Research Office(grant no.W911NF-15-1-0525);J.Y.was partly supported by a Stanford Graduate Fellowship.Single-crystal X-ray diffraction experiments were performed at beamline 12.2.1 at the advanced light source(ALS).The ALS is supported by the Director,Office of Science,Office of Basic Energy Science,of the U.S.Department of Energy(contract no.DE-AC02-05CH11231).

摘　　要：We have developed a rotaxane-based mechanophore system that is capable of breaking a mechanical bond and releasing small molecules via force-triggered rotaxane disassembly.In this design,a cyclobutane mechanophore was fused to the ring component of a rotaxane,constructed through a template-mediated synthesis in high yields.Upon opening the ring component,the rotaxane disassembled to release the axle molecule.We successfully demonstrated and quantified the force-triggered release of the axlemolecule in both solution and solid-state samples.

关 键 词：MECHANOCHEMISTRY ROTAXANE mechanophore polymer release of molecules 

分 类 号：O62[理学—有机化学]