海洛因滥用者血清铁代谢测定及其临床意义  

CLINICAL SIGNIFICANCE OF THE DETECTION OF SERUM IRON METABOLISM IN DRUG ADDICTS

作　　者：潘爱玲[1] 魏小文 陈晨 

机构地区：[1]海军广州疗养院检验科,广州510320 [2]广州海军421医院,广州510318

出　　处：《中国药物依赖性杂志》2002年第4期278-279,共2页Chinese Journal of Drug Dependence

摘　　要：目的 :探讨海洛因滥用时间对铁代谢的影响。方法 :对 83例海洛因滥用者按滥用时间分组 ,进行铁代谢指标检测 ,并与对照组进行均数两两比较t检验。结果 :滥用时间 >12个月者的血清铁 (SI)与正常对照组相比明显增加 (P <0 .0 5 ) ;总铁结合力 (TIBC)与正常对照组相比明显降低 (P <0 .0 5 ) ;滥用时间 >7个月者的转铁蛋白 (TRF)与正常对照组比较明显下降 (P <0 .0 5 ,P <0 .0 1)。结论Objective :To study the reactions of drugs on iron metabolism. Methods :83 drug addicts were divided into groups according to the duration of drug abuse and three indications of iron metabolism in serum were measured, T-test was adopted to compare the values between test groups and the control group. Results : Transferritin(TRF),serum iron(SI) and total iron binding capacity(TIBC) were correlated with the duration of drug abuse. The concentration of SI increased in accordance with the duration of drug abuse, while the concentration of TRF and TIBC decreased Conclusion : Chronic drug abuse affects normal iron metabolism in serum.

关 键 词：海洛因滥用 血清 铁代谢 测定 

分 类 号：R595.5[医药卫生—内科学]