左心疾病相关性肺动脉高压的生物标志物  

Biomarkers of pulmonary hypertension related to left heart disease

作　　者：胡长宇 吴晓梅[1] 臧思琪 HU Chang-yu;WU Xiao-mei;ZANG Si-qi(Department of Respiratory and Critical Care Medicine,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150081,China)

机构地区：[1]哈尔滨医科大学附属第二医院呼吸与危重症医学科,黑龙江哈尔滨150081

出　　处：《心血管康复医学杂志》2023年第3期261-264,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：肺动脉高压(PH)是临床常见疾病,可由多种心、肺疾病引起,其中以由左心疾病相关性肺动脉高压(PH-LHD)为最多见。目前,脑钠肽(BNP)和N基末端脑钠肽前体是指南推荐的诊断及判断心衰和PH预后的生物标志物。一些其他生物标志物也显示出在指导疾病管理方面与BNP互补。本文就PH-LHD生物标志物的应用作一综述。Pulmonary hypertension(PH)is a common clinical disease,which can be caused by a variety of heart and lung diseases,among which pulmonary hypertension related to left heart disease(PH-LHD)is the most common.At present,brain natriuretic peptide(BNP)and N-terminal pro-brain natriuretic peptide are recommended biomarkers for diagnosis and prognosis judgment of heart failure and PH by guidelines.Several other biomarkers have also shown to complement BNP in guiding disease management.The present article makes a review on application of PH-LHD biomarkers.

关 键 词：高血压 肺性 心力衰竭 利钠肽 脑 

分 类 号：R544[医药卫生—心血管疾病]