腹腔镜下胃十二指肠溃疡穿孔修补术的临床效果研究  

Clinical Effect of Laparoscopic Repair of Perforated Gastroduodenal Ulcer

作　　者：栾术亮 吕春梅[2] 门素梅 LUAN Shuliang;LYU Chunmei;MEN Sumei(Department of Endoscopy Center,Shandong Gaomi Second People's Hospital,Gaomi,Shandong Province,261500 China;Department of Clinical Laboratory,Shandong Gaomi People's Hospital,Gaomi,Shandong Province,261500 China;Department of Gynaecology and Obstetrics,Shandong Gaomi Second People's Hospital,Gaomi,Shandong Province,261500 China)

机构地区：[1]山东省高密市第二人民医院内镜中心,山东高密261500 [2]山东省高密市人民医院检验科,山东高密261500 [3]山东省高密市第二人民医院妇产科,山东高密261500

出　　处：《中外医疗》2023年第12期69-73,共5页China & Foreign Medical Treatment

摘　　要：目的分析腹腔镜下胃十二指肠溃疡穿孔修补术的临床效果。方法随机选取2019年3月—2021年3月山东省高密市第二人民医院收治的胃十二指肠溃疡患者80例为研究对象,依据随机数表法分两组,两组均40例。对照组行开腹修补术,观察组行腹腔镜下修补术治疗,对比两组术后恢复时间、疼痛评分、免疫功能、应激反应、并发症。结果两组患者手术时间对比,差异无统计学意义(P>0.05),但观察组其余临床相关指标优于对照组,差异有统计学意义(P<0.05);观察组患者各时段疼痛评分均低于对照组患者,差异有统计学意义(P<0.05);与术前相比,术后两组免疫功能均有所下降,对照组患者CD3^(+)、CD4^(+)两项免疫功能指标低于观察组,差异有统计学意义(P<0.05);与对照组患者相比,观察组应激反应指标水平均明显较低,差异有统计学意义(P<0.05);与对照组的20.00%相比,观察组术后并发症2.50%明显较低,差异有统计学意义(χ^(2)=4.507,P=0.034);观察组生活质量总分(88.24±2.15)分高于对照组(81.24±2.06)分,差异有统计学意义(t=14.868,P<0.001)。结论在腹腔镜下行胃十二指肠溃疡穿孔修补术可有效降低开腹手术的创伤性,有助于缩短患者术后恢复时间,且对免疫功能影响较小,术后并发症风险较低。Objective To analyze the clinical effect of laparoscopic repair of perforated gastroduodenal ulcer.Methods 80 patients with gastroduodenal ulcer admitted to the Gaomi Second People's Hospital from March 2019 to March 2021 were randomly selected as the study objects,and were divided into two groups according to random number table method,with 40 cases in both groups.The control group received open repair,and the observation group received laparoscopic repair.Postoperative recovery time,pain score,immune function,stress response and complications between two groups were compared.Results There was no statistically significant difference in operation time between the two groups(P>0.05),but other clinical related indexes in the observation group were significantly better than those in the control group,the difference was statistically significant(P<0.05).The pain scores of the observation group were lower than those of the control group at all time periods,the difference was statistically significant(P<0.05).Compared with before operation,the immune function of two groups decreased after operations,the levels of CD3^(+)and CD4^(+)immune function indexes in the control group were significantly lower than those in the observation group,the difference was statistically significant(P<0.05).Compared with patients in the control group,the levels of stress response in the observation group were significantly lower,the difference was statistically significant(P<0.05).The incidence of 2.50%in the observation group was significantly lower than that in the control group of 20.00%,the difference was statistically significant(χ^(2)=4.507,P=0.034).The total score of the observation group was(88.24±2.15)points,which was higher than that of the control group(81.24±2.06)points,the difference was statistically significant(t=14.868,P<0.001).Conclusion Laparoscopic repair of gastroduodenal ulcer perforation can effectively reduce the trauma of open surgery,help to shorten the postoperative recovery time of patients,and has little impa

关 键 词：腹腔镜 胃十二指肠溃疡穿孔 修补术 临床效果 

分 类 号：R4[医药卫生—临床医学]