明胶基缓释复合材料的制备及应用  

Preparation and Application of Gelatin-based Composites for Sustained Drug Release

作　　者：王忆娟 成纯伟 王婷 WANG Yi-juan;CHENG Chun-wei;WANG Ting(Department of Medicine,Wuhan College of Arts&Science,Wuhan 430345,Hubei,China)

机构地区：[1]武汉文理学院医学院,湖北武汉430345

出　　处：《合成材料老化与应用》2023年第3期115-118,共4页Synthetic Materials Aging and Application

基　　金：湖北省高等学校优秀中青年科技创新团队计划(T2022061);湖北省教育厅科学技术研究计划指导性项目(B2016462)。

摘　　要：明胶基复合材料既有良好的生物相容性和可降解性,又兼具机械强度高和多功能性,已成为缓释制剂的理想材料,在生物医学领域展现出广阔的应用前景。该文综述了明胶与其他材料复合制备缓释材料的方法,对近年来明胶基缓释复合材料在医药领域的应用现况进行了简述。最后,归纳了明胶基缓释复合材料面临的挑战和存在的技术问题,并对其未来进行了展望。Gelatin-based composites possesses the advantages of excellent biocompatibility,biodegradation,high mechanical strength,and multi-functionality,which has become the ideal materials for the sustained-release formulation and represents a promising application in the biomedical field.In this paper,the preparation methods of gelatin-based composites for sustained drug release were discussed,and their applications in medicine field in recent years were reviewed.Finally,the challenges and technical problems of gelatin-based composites were summarized,and their future development was prospected.

关 键 词：明胶 复合材料 缓释材料 

分 类 号：TB34[一般工业技术—材料科学与工程] TQ469[化学工程—制药化工]