老年脊柱手术中应用每搏量变异度指导液体治疗对术后认知功能的影响  

Influence of Stroke Volume Variation-guided Fluid Therapy on the Early Cognitive Function of Elderly Patients Following the Spinal Surgery

作　　者：郝伟 范惟 王佳妮 王超 HAO Wei;FAN Wei;WANG Jia-ni;WANG Chao(Department of Anesthesiology,Inner Mongolia Autonomous Region People's Hospital,Hohhot Inner Mongolia,010017,China)

机构地区：[1]内蒙古自治区人民医院麻醉科,内蒙古呼和浩特010017

出　　处：《中华养生保健》2023年第13期1-4,共4页CHINESE HEALTH CARE

基　　金：内蒙古自治区卫生健康科技计划项目(202201003);内蒙古自然科学基金(2020LH08048);内蒙古自治区留学人员创新创业启动支持计划(2020-13);内蒙古自治区人民医院博士科研启动资金项目(2021BS02)。

摘　　要：目的探究以每博量变异度为指导的液体疗法对老年脊柱患者术后早期认识功能的影响。方法抽取内蒙古自治区人民医院2020年2月—2021年2月收治的80例老年脊柱骨折患者作为研究对象,以随机抽样法为分组依据,分为研究1组(采用每博量变异度为指导的液体疗法)与研究2组(采用中心静脉血氧饱和度为指导的目标导向液体疗法),各40例,对干预效果进行分析比较。结果研究1组全心舒张末期容积(GEDV)、心排指数(CI)、胸腔内血容量指数(ITBVI)高于研究2组,血管外肺水指数(EVLWI)、外周血管阻力(SVRI)低于研究2组,差异有统计学意义(P<0.05)。两组术前简易精神状态评定量表(MMSE)评分比较,差异无统计学意义(P>0.05);研究1组术后6 h和术后24 h MMSE评分均高于研究2组,差异有统计学意义(P<0.05)。结论对老年脊柱患者采取以每搏量变异度为指导的液体疗法,可提升术后早期认知功能,此方法值得应用。Objective To study the influence of stroke volume variation-guided fluid therapy on the early cognitive function of elderly patients following the spinal surgery.Methods A total of 80 elderly patients of undergoing the spinal surgery from February 2020 to February 2021 in Inner Mongolia Autonomous Region People's Hospital were chosen as research samples.According to random sampling method,patients were divided into study group 1(stroke volume variation-guided fluid therapy)and study group 2(central venous oxygen saturation-guided fluid therapy),40 cases in each group.The intervention effects were probed.Results The global end-diastolic volume(GEDV),cardiac index(CI)and intrathoracic blood volume index(ITBVI)in study group 1 were higher than those of study group 2,but extravascular lung water index(EVLWI)and systemic vascular resistance index(SVRI)were lower than those of study group 2(P<0.05);before treatment,mini-mental state examination(MMSE)scores between groups were not significantly different(P>0.05),after 6 h and 24 h of treatment,MMSE scores in study group 1 were higher than those of study group 2(P<0.05).Conclusion The stroke volume variation-guided fluid therapy can stabilize the hemorheology,improve the early cognitive function.It is worthy of clinical application.

关 键 词：老年脊柱手术 每搏量变异度 液体疗法 认知功能 

分 类 号：R614[医药卫生—麻醉学]