血小板制剂联合去骨瓣减压术治疗高血压基底节区脑出血的效果  

Effect of Platelet Preparations Combined with Decompressive Craniectomy in Treatment of Hypertensive Basal Ganglia Intracerebral Hemorrhage

作　　者：邵义舜[1] 马娟娟[1] 卢蓉[1] Shao Yishun;Ma Juanjuan;Lu Rong(Department of Internal Medicine,Huazhong University of Science and Technology Hospital,Wuhan 430074,Hubei Province,China)

机构地区：[1]华中科技大学医院内科,湖北武汉430074

出　　处：《中国社区医师》2023年第15期30-32,共3页Chinese Community Doctors

摘　　要：目的:探讨血小板制剂联合去骨瓣减压术治疗高血压基底节区脑出血的效果。方法:选取2019年3月—2021年7月在华中科技大学医院接受治疗的120例高血压基底节区脑出血患者作为研究对象,随机分为对照组和试验组,各60例。所有患者接受开颅血肿清除联合去骨瓣减压术治疗,对照组采用阿司匹林治疗,试验组在对照组基础上于术前、术后1 d输注血小板制剂。比较两组再出血量及术后1 d血压水平、再出血率及病死率、昏迷程度及生活能力。结果:试验组再出血量少于对照组,术后1 d收缩压、舒张压、平均动脉压均低于对照组,差异有统计学意义(P<0.001)。试验组再出血率、病死率均低于对照组,差异有统计学意义(P<0.05)。术前,两组格拉斯哥昏迷量表(GCS)、生活能力评定量表(ADL)评分比较,差异无统计学意义(P>0.05);术后6个月,试验组GCS、ADL评分均高于对照组,差异有统计学意义(P<0.001)。结论:血小板制剂能够减少高血压基底节区脑出血患者术后再出血量,降低术后1 d血压水平、再出血率与病死率,提高患者的生活能力。Objective:To investigate the effect of platelet preparations combined with decompressive craniectomy in treatment of hypertensive basal ganglia intracerebral hemorrhage.Methods:From March 2019 to July 2021,120 patients with hypertensive basal ganglia intracerebral hemorrhage treated in Huazhong University of Science and Technology Hospital were selected as the study subjects.They were randomly divided into control group and experimental group,with 60 cases in each group.All patients received craniotomy for hematoma removal combined with decompressive craniectomy.The control group was treated with aspirin,and the experimental group was infused with platelet preparations before surgery and at 1 d after surgery on the basis of the control group.The amount of rebleeding,blood pressure levels at 1 d after surgery,the rebleeding rate and case fatality rate,the degree of coma and the living ability were compared between the two groups.Results:The amount of rebleeding in the experimental group was less than that in the control group,and the systolic blood pressure,diastolic blood pressure and mean arterial pressure at 1 d after surgery in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.001).The rebleeding rate and case fatality rate in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.05).Before surgery,there was no significant difference in the scores of Glasgow Coma Scale(GCS)and Activity of Daily Living(ADL)rating scale between the two groups(P>0.05).At 6 months after surgery,the GCS and ADL scores in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.001).Conclusion:Platelet preparations can reduce the amount of postoperative rebleeding in patients with hypertensive basal ganglia intracerebral hemorrhage,reduce blood pressure levels at 1 d after surgery,rebleeding rate and case fatality rate,and improve th

关 键 词：高血压基底节区脑出血 血小板制剂 阿司匹林 

分 类 号：R651.1[医药卫生—外科学]