右美托咪定与咪达唑仑在超声引导臂丛麻醉下小儿先天手指畸形矫形手术中的临床效果分析  

Clinical Effect Analysis of Dexmedetomidine and Midazolam in the Treatment of Pediatric Congenital Finger Deformity under Ultrasonic-guidedBrachial Plexus Anesthesia

作　　者：CAI Yanni YUZhiyuan XULing CAI Yanni;YU Zhiyuan;XU Ling(Department of anesthesiology,Dalian women and childrens medical center(Group),Dalian,Liaoning province 116021)

机构地区：[1]Department of anesthesiology,Dalian women and childrens medical center(Group),Dalian,Liaoning province 116021

出　　处：《中国伤残医学》2023年第9期29-32,80,共5页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:分析在超声引导臂丛麻醉下小儿先天手指畸形矫形手术中采用右美托咪定与咪达唑仑的临床应用价值。方法:随机选取我院2019年1月-2021年2月收治的小儿先天手指畸形矫形手术患儿80例,分为观察组( n=40 )和对照组( n=40),对照组采用右美托咪定(生产厂家:四川国瑞药业有限责任公司,批准文号:国药准字H20143195)进行麻醉,观察组采用右美托咪定联合咪达唑仑(生产厂家:江苏恩华药业股份有限公司,批准文号:国药准字H10980025 )进行麻醉,对比2组患儿手术后的苏醒时间、PACU滞留时间以及生命体征指标。结果:手术后,对比2组患儿的麻醉效果,观察组均显著优于对照组,且差异明显(P<0. 05),具有统计学意义;对比2组患儿的生命体征指标,观察组就平均动脉压、心率、血氧饱和度、呼吸频率均显著优于对照组,且差异明显(P<0. 05),具有统计学意义;观察组术后各时间段SF-MPQ评分及不良反应发生率均低于对照组,且差异明显(P<0. 05),具有统计学意义。结论:在小儿先天手指畸形矫形手术中采用右美托咪定联合咪达唑仑在超声引导臂丛麻醉,可有效给予患儿麻醉同时减少手术苏醒时间、PACU滞留时间,并且各项生命体征相对更稳定,术后不良反应少。Objective:To analyze the clinical application value of dexmedetomidine and midazolam in the treatment of pediatric con-genital finger deformity under ultrasonic-guided brachial plexus anesthesia.Methods:a total of 80 children with congenital finger de-formity undergoing orthopedic surgery in our hospital from January 2019 to February 2021 were randomly selected and assigned to the ob-servation group and control group.The control group was treated with dexmedetomidine(manufacturer:Sichuan Guorui Pharmaceutical Co.,LTD.,)Approval Number:The observation group was anesthetized with dexmedetomidine combined with midazolam(Jiangsu Nhwa Pharmaceutical Co.,Ltd.,Approval No.H10980025).The recovery time,PACU retention time and vital signs of the two groups after surgery were compared.Results:After surgery,comparing the anesthesia effect of the two groups of children,the observation group was significantly better than the control group and the difference was significant(P<0.05),with statistical significance;The vital signs of the two groups were compared,and the average arterial pressure,heart rate,oxygen saturation and respiratory rate in the observation group were significantly better than those in the control group,with significant differences(P<0.05).The SF-MPQ score and the inci-dence of adverse reactions in the observation group were lower than those in the control group at each postoperative time,and the differences were statistically significant(P<0.05).Conclusions:Ultrasound guided brachial plexus anesthesia with dexmedetomidine com-bined with midazolam can effectively give anesthesia to children in the correction of finger deformity of West Day,while reducing the op-eration recovery time and PACU retention time,and the vital signs are relatively stable,with fewer postoperative adverse reactions.

关 键 词：右美托咪定 咪达唑仑 麻醉 小儿先天手指畸形 

分 类 号：R614[医药卫生—麻醉学]