青少年特发性脊柱侧凸症发病机制的研究进展  

Research Advances on the Pathogenesis of Adolescent Idiopathic Scoliosis

作　　者：汪飞 佘瑞涛[1] 蔡其锐 林远方 WANG Fei;SHE Ruitao;CAI Qirui(Shenzhen traditional Chinese medicine hospital,Shenzhen,Guangzhou 518034)

机构地区：[1]深圳市中医院,广东深圳518034

出　　处：《中国伤残医学》2023年第9期89-94,共6页Chinese Journal of Trauma and Disability Medicine

基　　金：深圳市科技计划资助项目项目编号:JCYJ20210324111212035;深圳市政府医疗卫生三名工程项目项目编号:SZSM201612059。

摘　　要：侧凸是指由于某种原因造成脊柱一个或多个节段于冠状面上出现持久性偏离中线,形成带有弧度的脊柱畸形,其中发生于青春期及其前后的人群称为青少年特发性脊柱侧凸症。目前导致该病的病理生理机制尚未明确,涉及基因遗传、内分泌代谢、脊柱生物力学、神经肌肉系统、环境生活方式等多个方面。本文将对青少年特发性脊柱侧凸症的发病机制进行综述并开展相关讨论,以期为青少年特发性脊柱侧凸症患者临床研究提供理论指导和依据。Scoliosis refers to the permanent deviation of one or more segments of the spine from the midline on the coronal plane for some reason,resulting in a curvature of the spine,which occurs in and around puberty and becomes adolescent idiopathic spine Scoliosis.At present,the pathology physiological mechanism leading to the disease is not yet clear,involving many aspects such as genetic inheritance,endocrine metabolism,spinal biomechanics,nerve-muscle system,environmental lifestyle and so on.This article will review and discuss the pathogenesis of adolescent idiopathic scoliosis,in order to provide theoretical guidance and basis for clinical research on adolescent idiopathic scoliosis patients.

关 键 词：青少年特发性脊柱侧凸症 发病机制 遗传因素 生物力学 

分 类 号：R681.5[医药卫生—骨科学]