微波疗法联合中药灌肠治疗秋季腹泻患儿的疗效及机制研究  

Efficacy and Mechanism of Microwave Therapy Combined with Traditional Chinese Medicine Enema in Treatment of Children with Autumn Diarrhea

作　　者：张小坤 王祎波[1] 尹学永[1] ZHANG Xiaokun;WANG Yibo;YIN Xueyong(The Second Hospital of Qinhuangdao,Qinhuangdao 066600,Hebei,China)

机构地区：[1]秦皇岛市第二医院,河北秦皇岛066600

出　　处：《辽宁中医杂志》2023年第5期78-81,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：广东省中医药局科研项目(20151297)。

摘　　要：目的探讨微波疗法联合中药灌肠治疗秋季腹泻患儿的疗效及作用机制。方法选取时间:2019年1月-2022年1月,选取对象:60例该院收治的秋季腹泻患儿,分组依据:随机数字表法,将其分为观察组和对照组,均30例。对照组患儿接受常规治疗及中药灌肠,观察组患儿在此基础上加用微波疗法,两组均治疗7 d并随访3个月。比较两组患儿治疗后的临床效果;腹痛缓解时间、腹泻停止时间、住院时间、住院费用;治疗前后的T淋巴细胞亚群、白细胞计数(WBC),C-反应蛋白(CRP)、血糖水平及生活质量。结果治疗后,观察组临床总有效率(93.33%,28/30)与对照组(73.33%,22/30)相比较高;观察组腹痛缓解时间、腹泻停止时间、住院时间与对照组相比较短,住院费用与对照组相比较少;治疗后两组外周血CD_(3)^(+)、CD_(4)^(+)、CD_(4)^(+)/CD_(8)^(+)水平与治疗前比,均呈现升高趋势,其中观察组高于对照组;治疗后两组外周血CD8^(+)、血清WBC、CRP、血糖水平与治疗前比,均呈现降低趋势,其中观察组低于对照组,差异均有统计学意义(均P<0.05)。结论秋季腹泻患儿应用微波疗法联合中药灌肠治疗能减轻临床症状,抑制炎症反应,调节机体T淋巴细胞亚群,改善免疫功能,利于病情恢复。Objective To investigate the efficacy and mechanism of microwave therapy combined with traditional Chinese medicine enema in the treatment of children with autumn diarrhea.Methods From January 2019 to January 2022,60 children with autumn diarrhea admitted to the hospital were divided into observation group and control group according to the random number table method,30 cases in each.The children in the control group received conventional treatment and traditional Chinese medicine enema,while those in the observation group received microwave therapy on this basis.Both groups were treated for 7 d and followed up for 3 months.The clinical effects,the abdominal pain relief time,the diarrhea stop time,the hospitalization time,the hospitalization expenses,T lymphocyte subsets,white blood cell count(WBC),C-reactive protein(CRP),blood glucose and quality of life before and after treatment of the two groups were compared.Results After treatment,the total clinical effective rate(93.33%,28/30)of the observation group was higher than that of the control group(73.33%,22/30).Compared with those of the control group,the abdominal pain relief time,the diarrhea cessation time and the hospitalization time in the observation group were shorter than those in the control group,and the hospitalization expenses were less than those in the control group.After treatment,the levels of CD_(3)^(+),CD_(4)^(+) and CD_(4)^(+)/CD_(8)^(+) in peripheral blood of the two groups showed an increasing trend compared with those before treatment,and the levels of the observation group were higher than those of the control group.After treatment,the levels of peripheral blood CD8^(+),serum WBC,CRP and blood glucose in the two groups showed a decreasing trend compared with those before treatment,and those of the observation group were lower than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion The application of microwave therapy combined with traditional Chinese medicine enema in children with autumn d

关 键 词：秋季腹泻 微波疗法 中药灌肠 炎症反应 T淋巴细胞亚群 

分 类 号：R723.11[医药卫生—儿科]