通塞脉片联合黄柏液外敷治疗气阴两虚兼血瘀型糖尿病足的临床研究  

Clinical Study on Treatment of Diabetes Foot with Deficiency of Both Qi and Yin and Blood Stasis by External Application of Tongsaimai Tablet(通塞脉片)and Huangbai Liquid(黄柏液)

作　　者：关婕婷 刘鹏 王彦辉 呼永河[2] GUAN Jieting;LIU Peng;WANG Yanhui;HU Yonghe(Shunyi Hospital,Beijing Hospital of Traditional Chinese Medicine,Beijing 101300,China;General Hospital of Chengdu Military Region,Chengdu 610083,Sichuan,China)

机构地区：[1]北京中医医院顺义医院,北京101300 [2]成都军区总医院,四川成都610083

出　　处：《辽宁中医杂志》2023年第5期159-163,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：首都卫生发展科研专项项目-青年优才项目(2022-2-7104)。

摘　　要：目的探讨通塞脉片联合黄柏液外敷治疗气阴两虚兼血瘀型糖尿病足的临床研究。方法该研究采用对照分析的方式,选取2018年1月-2020年5月于该院就诊的气阴两虚兼血瘀型糖尿病足患者88例,收集资料,依据数字表法分为两组,对照组(45例)和观察组(43例)。两组患者基础治疗均相同,对照组患者予以复方黄柏液外敷;观察组患者予以通塞脉片联合黄柏液外敷,持续治疗4周。4周疗程结束后评价中医疗效和西医疗效,治疗前后分别评价中医证候积分和足背动脉彩超指标。结果对照组患者的中医总有效率为80.00%(36/45)。观察组患者的中医总有效率为95.35%(41/43)。对照组的中医总有效率低于观察组,差异有统计学意义(P<0.05)。对照组患者的西医总有效率为73.33%(33/45),观察组患者的西医总有效率为90.70%(39/43)。对照组的西医总有效率低于观察组,差异有统计学意义(P<0.05)。与治疗前比,两组治疗后中医主证、次证、舌象、脉象评分均降低;而且观察组治疗后中医主证、次证、舌象、脉象评分均低于对照组,差异有统计学意义(P<0.05)。与治疗前比,两组治疗后足背动脉的血管内径、血流量、RI和PI均升高;而且观察组治疗后足背动脉的血管内径、血流量、阻力指数(RI)和搏动指数(PI)均高于对照组,差异有统计学意义(P<0.05)。结论通塞脉片联合黄柏液外敷对于气阴两虚兼血瘀型糖尿病足的中西医疗效显著,可以改善中医证候和足部血流动力学。Objective To explore the clinical study of Tongsaimai Tablet(通塞脉片)combined with Huangbai Liquid(黄柏液)in the treatment of diabetes foot with deficiency of both Qi and Yin and blood stasis.Methods A total of 88 patients with diabetes foot of deficiency of both Qi and Yin and blood stasis type treated in the hospital from January 2018 to May 2020 were selected by means of comparative analysis.The data was collected and the patients were divided into two groups according to the digital table method:the control group(45 cases)and the observation group(43 cases).The basic treatment of the two groups was the same,and the patients in the control group were treated with Compound Huangbai Liquid externally.The patients in the observation group were treated with Tongsaimai Tablet combined with Huangbai Liquid for 4 weeks.After 4 weeks of treatment,the curative effect of traditional Chinese medicine and Western medicine was evaluated.Before and after treatment,the integral of traditional Chinese medicine syndrome and the color Doppler index of dorsalis pedis artery were evaluated respectively.Results The total effective rate of traditional Chinese medicine in the control group was 80.00%(36/45),and the total effective rate of traditional Chinese medicine in the observation group was 95.35%(41/43).The total effective rate of traditional Chinese medicine in the control group was lower than that of the observation group,and the comparison was statistically significant(P<0.05).The total effective rate of Western medicine in the control group was 73.33%(33/45),and that in the observation group was 90.70%(39/43),and the total effective rate of Western medicine in the control group was lower than that of the observation group,and the comparison was statistically significant(P<0.05).Compared with those before treatment,the scores of main syndrome,secondary syndrome,tongue and pulse of the two groups decreased after treatment.Moreover,the scores of main syndrome,secondary syndrome,tongue and pulse in the observation grou

关 键 词：通塞脉片 黄柏液外敷 气阴两虚兼血瘀型 糖尿病足 足部血流动力学 

分 类 号：R587.2[医药卫生—内分泌]