超声造影在原发性甲状旁腺功能亢进症术前定位中的应用  

Application of contrast-enhanced ultrasonography in preoperative localization of primary hyperparathyroidism

作　　者：陈蓉 王鸥 朱庆莉[2] 邢小平 CHEN Rong;WANG Ou;ZHU Qing-li;XING Xiao-ping(Department of Endocrinology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Key Laboratory of Endocrinology,National Health and Family Planning Commission,Beijing 100730,China;Department of Ultrasonography,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院、北京协和医学院、北京协和医院内分泌科,国家卫生健康委员会内分泌重点实验室,北京100730 [2]中国医学科学院、北京协和医学院、北京协和医院超声医学科,北京100730

出　　处：《中华骨质疏松和骨矿盐疾病杂志》2023年第1期72-79,共8页Chinese Journal Of Osteoporosis And Bone Mineral Research

基　　金：中央高水平医院临床科研业务费资助(2022-PUMCH-B-014)。

摘　　要：原发性甲状旁腺功能亢进症(primary hyperparathyroidism,PHPT)是一种常见的内分泌疾病,可累及骨骼、肾脏等多器官系统。手术是治愈PHPT的唯一方法,因此,术前对病变的甲状旁腺组织精准定位对于手术十分重要。目前仍有部分病例术前定位诊断较为困难。甲状旁腺超声造影(contrast-enhanced ultrasonography,CEUS)是一种新的检查手段,正逐渐用于PHPT的术前定位,尤其用于常规超声与99m Tc-甲氧基异丁基异腈(99T cm-sestamibi,MIBI)结果不一致、合并甲状腺病变等情况。本文就甲状旁腺CEUS在PHPT术前定位中的应用进行综述,以期提高临床医师对该项检查技术的认识。Primary hyperparathyroidism(PHPT)is one of the common endocrine diseases that impairs multiple systems including bone and kidneys.Surgery is the only way to cure PHPT,for which the pre-surgical location of parathyroid lesions is important.Up to now,there are still a small proportion of cases of PHPT facing difficulties in presurgical localization.Contrast-enhanced ultrasonography(CEUS)is a new clinically applicable imaging method for the preoperative localization of parathyroid lesions,especially for the cases with inconsistent results of conventional ultrasound,and 99T cm-sestamibi(MIBI),or those with concomitant thyroid lesions,etc.This article reviews the application of CEUS in the preoperative localization of parathyroid lesions in PHPT to improve the clinicians'understanding.

关 键 词：原发性甲状旁腺功能亢进症 术前定位 超声造影 

分 类 号：R582[医药卫生—内分泌]