肠道因素对胆石病防治的作用  

Factors related to intestine have a role in prevention and treatment for gallstone disease

作　　者：蒋兆彦[1,2] 沈惟一 胡海 JIANG Zhaoyan;SHEN Weiyi;HU Hai(Center of Gallbladder Disease,Shanghai East Hospital,Tongji University,Shanghai 200120,China;Institute of Gallstone Disease,Tongji University School of Medicine,Shanghai 200331,China)

机构地区：[1]同济大学附属东方医院胆石病中心,上海200120 [2]同济大学医学院胆石病研究所,上海200331

出　　处：《外科理论与实践》2023年第2期91-93,共3页Journal of Surgery Concepts & Practice

基　　金：国家自然科学基金(82070654);上海市浦东新区卫生健康委员会临床特色学科建设计划(PWYts2021-06)。

摘　　要：胆石病是一种常见外科疾病。肠道相关因素在胆石病发生过程中的作用日益受到重视。影响胆固醇结石形成的主要因素包括胆固醇吸收、胆汁酸浓度、肠道菌群改变等,均与肠道相关。正确认识胆石形成中的肠道因素,有助于胆石病的防治。针对肠道不同靶点的治疗方法,未来或许在胆石病预防和胆囊切除术后治疗中起到重要作用。Gallstone is a common surgical disease.The factors which related to intestine during the process of gall-stone formation have attracted increasing attention.The main factors affecting the formation of cholesterol gallstone includ-ing cholesterol absorption,bile acid concentration,gut microbiota changing,are all related to the intestine.A correct under-standing of the factors related to intestine during gallstone formation is helpful for the prevention and treatment of gallstone disease.In future,different targets related to intestine may play an important role in both prevention of gallstone disease and post-cholecystectomy management.

关 键 词：胆石病 肠道吸收 胆固醇 胆汁酸 

分 类 号：R657.42[医药卫生—外科学]