青蒿素缓释微粒对铜绿微囊藻的抑制机理研究  

Study on The Inhibition Mechanism of Artemisinin Slow-release Particles Against Microcystis Aeruginosa

作　　者：张铮惠 李霞 张建华[2] 陈旭清 倪利晓[3,4] ZHANG Zheng-hui;LI Xia;ZHANG Jian-hua;CHEN Xu-qing;NI Li-xiao(Wuxi River And Lake Management and Water Resources Management Center,Wuxi 214071,China;Ecological River and Lake Division Water Resources Department of Jiangsu Province,Nanjing 210029,China;College of Environment,Hohai University,Nanjing 210098,China;Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes,Ministry of Education,Hohai University,Nanjing 210098,China)

机构地区：[1]无锡市河湖治理和水资源管理中心,江苏无锡214071 [2]江苏省水利厅生态河湖处,江苏南京210029 [3]河海大学环境学院,江苏南京210098 [4]河海大学浅水湖泊综合治理与资源开发教育部重点实验室,江苏南京210098

出　　处：《环境科技》2023年第3期30-34,41,共6页Environmental Science and Technology

基　　金：江苏省水利科技项目(2022063)。

摘　　要：蓝藻水华暴发具有范围广、频次高、生物量高等特征,易造成水生系统结构和功能严重失衡。化感物质因其具有抑藻高效性、安全性和经济性而引起越来越多的关注和研究。将化感物质—青蒿素制备成具有持续抑藻效果的青蒿素缓释微粒并研究其对铜绿微囊藻的生长影响。研究结果表明,质量浓度为0.2 g/L的青蒿素可以抑制叶绿素a合成进而抑制藻细胞光合作用;诱导藻细胞产生过量活性氧(ROS),对藻细胞膜的通透性产生不可逆的损伤,从而抑制藻细胞的正常生长。Cyanobacteria bloom outbreaks are characterized by wide range,high frequency and high biomass,resulting in serious imbalance of aquatic system structure and function.Allelopathic substances have attracted more and more attention because of their high efficiency,safety and economy of algal inhibition.In this study,artemisinin was prepared into artemisinin slow-release particles with continuous algal inhibitory effect and its effect on the growth of M.aeruginosa was studied.The results showed that 0.2 g/L artemisinin could inhibit chlorophyll a synthesis and thus photosynthesis of algal cells.Induced algal cells to produce excessive reactive oxygen species(ROS),resulting in irreversible damage to the permeability of algal cell membrane,thus inhibiting the normal growth of algal cells.

关 键 词：青蒿素缓释微粒 铜绿微囊藻 光合作用 活性氧 

分 类 号：X5[环境科学与工程—环境工程]