血清及糖皮质类固醇诱导的蛋白激酶在糖尿病发生发展中作用的研究进展  

Research progress on the role of SGK in the development of diabetes mellitus

作　　者：韩迪 庄妍 孟峻[1] HAN Di;ZHUANG Yan;MENG Jun(Department of Clinical Laboratory,Affiliated Hospital of Inner Mongolia Medical University,Huhehaote 010050,China)

机构地区：[1]内蒙古医科大学附属医院检验科,呼和浩特010050

出　　处：《中国糖尿病杂志》2023年第5期394-397,共4页Chinese Journal of Diabetes

基　　金：内蒙古自然科学基金(2021MS08158)。

摘　　要：DM是常见内分泌系统疾病,发病率和病死率逐年升高。血清及糖皮质类固醇诱导的蛋白激酶(SGK)包括SGK1、SGK2、SGK3亚型,均在DM及其并发症中发挥重要调控作用。本文对SGK在DM发生发展中作用的研究进展进行综述,旨在为临床防治DM及其并发症提供依据。Diabetes mellitus(DM)is a common metabolic disease.In recent years,the incidence and mortality of DM has increased year by year.The serum and glucocorticoid induced protein kinase family(SGK)including SGK1,SGK2 and SGK3,play an important regulatory role in the development of DM and its complications.This article reviews the research progress of the SGK in order to provide basis for clinical prevention and treatment of DM and its complications.

关 键 词：糖尿病 血清及糖皮质类固醇诱导的蛋白激酶 糖尿病并发症 糖尿病肾脏疾病 

分 类 号：R587.1[医药卫生—内分泌]