1990—2019年我国焦虑症疾病负担及变化趋势分析  

Analysis on burden and variation trends of anxiety disorders in China from 1990-2019

作　　者：王志勇[1] 范转转 杨华凤[3] 徐斐[1] 程云凤 王美兰[1] WANG Zhi-yong;FAN Zhuan-zhuan;YANG Hua-feng;XU Fei;CHENG Yun-feng;WANG Mei-lan(Department of Basic Public Health Service,Nanjing Municipal Center for Disease Control and Prevention,Nanjing Jiangsu,210003,China;Material Department,Nanjing Municipal Center for Disease Control and Prevention,Nanjing Jiangsu,210003,China;Science and Education Department,Nanjing Municipal Center for Disease Control and Prevention,Nanjing Jiangsu,210003,China)

机构地区：[1]南京市疾病预防控制中心基本公共卫生科,江苏南京210003 [2]南京市疾病预防控制中心物资科,江苏南京210003 [3]南京市疾病预防控制中心科教科,江苏南京210003

出　　处：《职业与健康》2023年第9期1165-1170,1175,共7页Occupation and Health

基　　金：南京市卫生科技发展专项资金项目(GBX21213)。

摘　　要：目的 分析1990—2019年我国焦虑症的疾病负担及其变化趋势,为焦虑症的科学防控提供依据。方法 利用2019全球疾病负担数据库中国人群焦虑症的相关数据,采用病例数与发病率、患病例数与患病率、伤残调整生命年(disabilityadjusted life years,DALYs)与DALYS率等指标描述分析1990—2019年我国人群焦虑症的疾病负担,采用Joinpoint回归估算年度变化百分比(annual percent change,APC)和平均年度变化百分比(average annual percent change,AAPC)分析1990—2019年我国人群焦虑症疾病负担的变化趋势。结果 2019年我国焦虑症的发病人数、患病人数、DALYs分别为728.56万人、4784.22万人和321.60万人年,与2009相比年分别增长了9.27%、14.76%与13.08%;发病率、患病率、DALYs率分别为512.23/10万、3 363.60/10万和321.60/10万,与2009年相比分别降低了9.06%、4.49%和5.89%。女性发病率、患病率和DALYs率均高于男性,≥70岁组的疾病负担高于其他年龄组。1990—2019年我国焦虑症的标化发病率(AAPC=-0.19%,P<0.01)、标化患病率(AAPC=-0.31%,P<0.01)和标化DALYs率(AAPC=-0.29%,P<0.05)均呈下降趋势。结论 1990—2019年我国焦虑症的疾病负担整体呈下降趋势,不同性别、年龄的疾病负担存在差异。但是近年来开始出现回升,在生活节奏不断加快、老龄化等的影响下,焦虑症的疾病负担可能会持续加重,今后应加强对女性、儿童、青少年和老年等重点人群的干预,降低焦虑症对人群健康的危害。Objective To estimate the disease burden and variation trend of anxiety disorders from 1990 to 2019 in China,provide an evidence for scientific prevention and control of anxiety disorders.Methods The data of anxiety disorders in Chinese population were extracted from the database of the Global Burden of Disease Study 2019(GBD2019).The disease burden of anxiety disorders in China from 1990 to 2019 was described by incident case number and incidence rate,prevalent case number and prevalence rate,disability-adjusted life year(DALYS)and DALYS rate.The Joinpoint regression model was introduced to calculate the annual change(APC)and the average annual change(AAPC)to assess temporal trend of anxiety disorders burden from 1990 to 2019 in China.Results In 2019,the number of incident and prevalent cases,as well as DALYs in China were 7285600 persons,47842200 persons,and 3216000 person-years,respectively,with a 9.27%,14.76%and 13.08%rise,respectively,relative to that in 2009.The incidence,prevalence and DALY rates were 512.23/100000,3363.60/100000 and 321.60/100000,respectively,with a 9.06%,4.49%and 5.89%decline,respectively,relative to that in 2009.The incidence,prevalence and DALYs rates among females were higher than each of those for males,and the disease burden was higher in≥70 years old group than in the other age groups.From 1990 to 2019,the standardized incidence(AAPC=-0.19%,P<0.01),standardized prevalence(AAPC=-0.31%,P<0.01)and standardized DALYs(AAPC=-0.29%,P<0.05)of anxiety disorders showed a decreasing trend in China.Conclusions The overall disease burden of anxiety disorders decrease from 1990 to 2019 in China,with gender and age differences.However,in recent years,there has been a rebound.The burden of anxiety disorders may continue to increase under the influence of the accelerating pace of life and aging.In the future,it is necessary to strengthen intervention in key populations such as women,children,adolescents,and the elderly to reduce the harm of anxiety disorders to population health.

关 键 词：焦虑障碍 疾病负担 联结点回归模型 变化趋势 

分 类 号：R195[医药卫生—卫生统计学]