生物标志物在特应性皮炎中的研究进展  

Research Progress of Biomarkers in Atopic Dermatitis

作　　者：李俊龙 田歆 何素玲 黄琼霄 刘玉梅 王建琴 LI Junlong;TIAN Xin;HE Suling;HUANG Qiongxiao;LIU Yumei;WANG Jianqin(Institute of Dermatology,Guangzhou Medical University,Guangzhou Institute of Dermatology,Guangzhou 510095,China)

机构地区：[1]广州市皮肤病防治所,广州医科大学皮肤病研究所,广东广州510095

出　　处：《中国皮肤性病学杂志》2023年第5期605-610,共6页The Chinese Journal of Dermatovenereology

基　　金：广东省医学科研基金项目(B2020068)。

摘　　要：在过去的几十年间,随着对特应性皮炎(AD)发病机制的深入研究,发现了许多与疾病相关的生物标志物,认识到AD患者存在显著的异质性。如今为了满足精准医学尤其是靶向治疗的需求,研究者致力于通过生物标志物对AD患者进行亚型的划分。本文将对生物标志物在AD中的研究进展和价值进行阐述,同时将这些标志物划分为识别性与监测性两类进行总结。Over the past decades,as research into the pathogenesis of atopic dermatitis(AD)has intensified,many disease-related biomarkers have been identified and significant heterogeneity in AD patients has been recognized.To meet the needs of precision medicine,especially targeted therapies,we are nowadays dedicated to the subtyping of AD patients by biomarkers.In this paper,we will describe the progress and value of biomarker research in AD,and also summarize these markers into two categories:identification and monitoring.

关 键 词：特应性皮炎 生物标志物 精准医学 内表型 

分 类 号：R758.2[医药卫生—皮肤病学与性病学] R446.1[医药卫生—临床医学]