中医眼科升清降浊用方用药规律分析  

Analysis on Ascending Clear and Descending Turbid Prescription of Ophthalmology of Traditional Chinese Medicine

作　　者：邱心悦 赖思艺 张瑞芬 刘光辉[1,2] Qiu Xinyue;Lai Siyi;Zhang Ruifeng;Liu Guanghui(Fujian Principal People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350004,China;Eye Institute of Integrated Chinese and Western Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou 350004,China;Dehua Hospital of Chinese Medicine,Quanzhou 362500,China)

机构地区：[1]福建中医药大学附属人民医院,福建福州350004 [2]福建中医药大学中西医结合眼科研究所,福建福州350004 [3]德化县中医院,福建泉州362500

出　　处：《亚太传统医药》2023年第6期155-160,共6页Asia-Pacific Traditional Medicine

基　　金：福建中医药大学优势学科专项课题(X2022018-专项);国家自然科学基金面上项目(81774369)。

摘　　要：目的:探索中医眼科应用升清降浊法治疗眼病的用方用药规律。方法:检索中国知网(CNKI)、维普、万方数据库中1982年1月-2022年6月与中医眼科临床应用升清降浊法相关的文献,再将文献中所含方药组成录入中医传承辅助平台建立数据库,进行方剂的归类统计分析并对其中所含中药的使用频次、用药模式、药物属性、组方规律进行统计和规则分析。结果:共纳入文献82篇,纳入方剂184首,涉及中药207味。使用频次最高的方剂种类前3位分别为补益剂(87次,47.28%)、祛湿剂(26次,14.13%)、和解剂(26次,14.13%)。高频中药(使用频次≥20次)有26味,排名前5位的分别为甘草(87次,4.752%)、茯苓(87次,4.752%)、当归(72次,3.932%)、白术(63次,3.441%)和白芍(49次,2.676%)。四气以温性药最多,占比40.20%;五味以甘味药为首,占比34.89%;归经以脾经最多,占比18.24%。关联规则分析药对出现频次排在前3位的分别是甘草-茯苓、白术-甘草、白术-茯苓。结论:中医眼科临床应用升清降浊法的方剂以补益剂居多,使用药物以补益类药物为主,性多甘温,归脾经,配伍时以甘草、茯苓为核心组成药对,但在临床应用时还需根据辨证论治,选择性使用。Objective:To explore the rules of prescription and medication for eye diseases based on the method of ascending clear and descending turbid in ophthalmology of Traditional Chinese Medicine(TCM).Methods:The relevant literatures of ophthalmology of TCM,related to the clinical application of ascending clear and descending turbid and published from January 1982 to June 2022,were searched from CNKI,VIP and Wanfang database,then the prescriptions of the literatures were entered into the auxiliary platform for inheritance of traditional Chinese medicine to establish a database.Classification and statistical analysis of the prescriptions,as well as the analysis of use frequency,use mode,the attribute of Chinese herbal medicine(CHM),were carried out to explore the rules underlying the literatures.Results:184 prescriptions of 82 literatures involving 207 CHM were included.The top three prescriptions in terms of usage frequency are tonics(87 times,47.28%),dehumidifiers(26 times,14.13%)and conciliators(26 times,14.13%).There are 26 high-frequency Chinese medicines(frequency≥20 times).The top five are licorice(87 times,4.752%),Poria Cocos(87 times,4.752%),Angelica sinensis(72 times,3.932%),Atractylodes macrocephala(63 times,3.441%)and Paeonia alba(49 times,2.676%).Among them,the use frequency of four Qi warming CHM was the highest,accounting for 40.20%.Among the five flavors,sweet herbs were used most frequently,accounting for 34.89%.Spleen meridian is the most important meridian,accounting for 18.24%.The top 3 pairs in terms of analysis of compatibility rules of CHM are licorice Poria cocos;Atractylodes macrocephala licorice;Atractylodes macrocephala Poria cocos.Conclusion:Most of the prescriptions used in the clinical application of the method of raising the clear and lowering the turbid in ophthalmology of TCM are tonics.And the drugs used are mainly tonic drugs,warm and sweet,entering the spleen meridian.When they are compatible,licorice and poria cocos are the core drug pairs,but it needs to be used selectively accordi

关 键 词：升清降浊 中医眼科 规则分析 方药应用 

分 类 号：R276.7[医药卫生—中医五官科学]