阿尔茨海默病患者行为特征与照顾者负担水平的相关性研究  

Correlation between behavioral characteristics of Alzheimer’s disease patients and caregiver burden level

作　　者：夏晴晴 赵桂琴 XIA Qingqing;ZHAO Guiqin(Department of Nosocomial Infection Management,Shaoxing Seventh People’s Hospital,Shaoxing,312000,Zhejiang,China;First Ward of Geriatric,Shaoxing Seventh People’s Hospital,Shaoxing,312000,Zhejiang,China)

机构地区：[1]绍兴市第七人民医院院感科,浙江绍兴312000 [2]绍兴市第七人民医院老年一病区,浙江绍兴312000

出　　处：《中国现代医生》2023年第16期59-62,共4页China Modern Doctor

基　　金：绍兴市级医卫类科技计划项目(2020A13050)。

摘　　要：目的探讨阿尔茨海默病(Alzheimer’s disease,AD)患者行为特征与照顾者负担水平的相关性。方法选取2021年2月至2022年2月绍兴市第七人民医院收治的116例AD患者及其照顾者为调查对象,并采用自制一般资料调查表进行调查。采用照顾者负担问卷(caregiver burden inventory,CBI)评价照顾者负担水平,采用神经精神问卷(neuropsychiatric inventory,NPI)评价AD患者痴呆的行为精神症状(behavioral and psychological symptom of dementia,BPSD),并对NPI中12个因子进行降维处理,提出主成分,采用Pearson相关分析探讨AD患者行为特征与照顾者负担水平的相关性。结果AD患者的NPI评分(21.37±3.07)分,照顾者的CBI评分(40.51±14.29)分;主成分分析显示,KMO测量值为0.895,Bartlett的球形检验统计显著<0.001,模型的拟合度优,使用基于12种BPSD症状严重程度的因素分析,提取精神病症状、身体行为症状、多动症状三个因素,三个因素的总解释力为总方差的72.30%;照顾者CBI评分与NPI中身体行为症状评分(r=0.698,P<0.001)、精神病症状评分(r=0.564,P<0.001)、多动症状评分(r=0.470,P<0.001)及总分(r=0.726,P<0.001)均呈正相关。结论AD患者的照顾者负担相对较重,AD患者行为特征与照顾者负担呈正相关。Objective To explore the correlation between behavioral characteristics of Alzheimer’s disease(AD)patients and caregiver burden level.Methods A total of 116 AD patients and their caregivers in Shaoxing Seventh People’s Hospital from February 2021 to February 2022 were selected as the survey subjects,and a self-made general information questionnaire was used for the investigation.Caregiver burden inventory(CBI)was used to evaluate the caregiver burden level,and neuropsychiatric inventory(NPI)was used to evaluate the behavioral and psychological symptom of dementia(BPSD)of AD patients,and to reduce the dimensionality of the 12 factors in the NPI,propose principal components,and use Pearson correlation to analyze the correlation between AD patients’behavioral characteristics and caregiver burden levels.Results The NPI score of AD patients was(21.37±3.07)points,and the CBI score of caregivers was(40.51±14.29)points.Principal component analysis showed that the KMO measurement value was 0.895,and the statistical significance of Bartlett’s sphere test was less than 0.001.The fitting degree of the model was excellent.Using factor analysis based on the severity of 12 BPSD symptoms,psychotic symptoms,physical behavior symptoms and hyperactivity symptoms were extracted,and the total explanatory power of the three factors was 72.30%of the total variance.The CBI score of the caregivers of AD patients and physical behavioral symptom score(r=0.698,P<0.001),psychotic symptom score(r=0.564,P<0.001),hyperactivity symptom score(r=0.470,P<0.001)and total score(r=0.726,P<0.001)were significantly positively correlated.Conclusion The caregiver burden of AD patients is relatively heavy,and the behavioral characteristics of AD patients are positively correlated with the caregiver burden.

关 键 词：阿尔茨海默病 照顾者 行为特征 照顾负担 

分 类 号：R395[哲学宗教—心理学]