温针灸联合腰痛宁胶囊治疗椎间盘源性下腰痛的疗效分析  

Efficacy Analysis of Warm Acupuncture Combined with Yaotongning Capsule in the Treatment of Discogenic Low Back Pain

作　　者：蔡建辉 吴振华 李洪涛[1,3] 孙晓伟[1,3] Cai Jianhui;Wu Zhenhua;Li Hongtao;Sun Xiaowei(Heilongjiang University of Traditional Chinese Medicine,Heilongjiang,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]河北中医学院,河北石家庄050020 [3]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040

出　　处：《中国中医急症》2023年第6期1062-1065,共4页Journal of Emergency in Traditional Chinese Medicine

基　　金：黑龙江省博士后科研启动基金(LBH-Q19182);黑龙江省卫生健康委科研课题(20220404071118);黑龙江省中医药科研项目(ZHY2020-125)。

摘　　要：目的观察温针灸联合腰痛宁胶囊治疗椎间盘源性下腰痛的临床疗效并探讨其作用机制。方法80例患者随机分为观察组与对照组各40例。在常规治疗基础上,对照组口服腰痛宁胶囊,观察组在对照组基础上采用温针灸。比较两组患者治疗前后McGill疼痛量表[包括疼痛评级指数(PRI)、疼痛状况(PPI)和视觉模拟量表(VAS)评分]、Oswestry功能障碍指数(ODI)及改良日本骨科协会评估量表(JOA)评分。观察对比炎症因子肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白细胞介素-6(IL-6)。结果观察组总有效率为87.50%,高于对照组的70.00%(P<0.05)。两组治疗2周、4周后患者McGill疼痛量表评分(PRI、PPI和VAS疼痛评分)和ODI功能障碍指数与治疗前比较,评分均下降(P<0.05),且观察组下降均较对照组更明显(P<0.05)。两组患者JOA评分与治疗前比较升高(P<0.05),且观察组高于对照组(P<0.05)。两组治疗2周、4周后炎性因子水平较治疗前均降低(P<0.05),且观察组均低于对照组(均P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。出现不良反应后,立即停止治疗,停止治疗后其不良反应均消失。结论温针灸联合腰痛宁胶囊治疗椎间盘源性下腰痛的临床疗效较好,可有效缓解腰痛、功能障碍症状,抑制炎性因子的释放和聚集。Objective:To observe the difference in clinical efficacy of warming acupuncture combined with Yao-tongning Capsule in the treatment of discogenic low back pain,and to investigate its mechanism of action.Meth-ods:A total of 80 patients with intervertebral discogenic low back pain were randomly divided into the observa-tion group and control group,40 cases in each group.On the basis of general basic treatment,the control group was treated with Yaotongning Capsule orally,while the observation group was treated with warm acupuncture on the basis of the control group.The McGill Pain Scale(including PRI,PPI and VAS pain scores),ODI Dysfunction Index and Modified JOA Score were observed and compared between the two groups before and after treatment.The inflammatory factors tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),and interleukin-6(IL-6)were observed and compared.Results:The total effective rate in the observation group was 87.50%,which was higher than 70.00%in the control group(P<0.05).After 2 weeks and 4 weeks of treatment,the McGill Pain Scale scores(PRI,PPI and VAS pain scores)and ODI Dysfunction Index decreased(all P<0.05)compared with before treatment,and the observation group decreased more significantly than the control group(all P<0.05).The JOA score was higher in both groups than before treatment(P<0.05),and the observation group was higher than that in the control group(P<0.05).After 2 weeks and 4 weeks of treatment,the levels of inflammatory factors in both groups were reduced compared with those before treatment(P<0.05),and the observation group was lower than that of the control group(all P<0.05).The incidence of adverse reactions between the two groups was not statisti-cally significant(P>0.05).After the occurrence of adverse reactions,treatment was stopped immediately,and the adverse reactions disappear after stopping treatment.Conclusion:The clinical efficacy of warm acupuncture com-bined with Yaotongning Capsule in the treatment of low back pain caused by intervertebral disc is good,whic

关 键 词：椎间盘源性下腰痛 温针灸 腰痛宁胶囊 

分 类 号：R681.53[医药卫生—骨科学]