电沉积负载氧化石墨烯原位还原金纳米粒子@多金属氧簇薄膜及DPV法检测血液中的尿酸  

In-situ Reduction of Gold Nanoparticles@Polyoxometalates Film on Electrodeposited GO and Detection of Uric Acid in Blood by DPV

作　　者：鲍雅妍 鲍善霞 张健 冯锋[1] BAO Ya-yan;BAO Shan-xia;ZHANG Jian;FENG Feng(School of Chemistry and Chemical Engineering,Shanxi Datong University,Datong Shanxi,037009)

机构地区：[1]山西大同大学化学与化工学院,山西大同037009

出　　处：《山西大同大学学报（自然科学版）》2023年第3期1-5,共5页Journal of Shanxi Datong University(Natural Science Edition)

基　　金：2019年山西大同大学校级科研项目[2019K3];国家自然科学基金资助项目[21375083]。

摘　　要：采用电沉积法负载的氧化石墨烯(Graphene Oxide,GO)薄膜,在电化学辅助还原的作用下成功制备了还原态氧化石墨烯(Reduced Graphene Oxide,rGO)/金纳米粒子(Au NPs)@多金属氧簇(P2W18)纳米杂化薄膜。制备过程可在1 h内完成。所制备的{PEI/rGO/Au@P_(2)W_(18)}电极仅负载单层催化剂,DPV法检测尿酸(UA)具有良好的线性关系(5.00×10^(-7)~1.50×10^(-4) mol/L),较低的检出限(1.24×10^(-8)mol/L),优良的灵敏度85.98A/(mol/cm^(2)),重现性好。rGO、P_(2)W_(18)和Au NPs的协同作用,尤其是在薄膜制备过程中发生的电子转移增强了催化剂的催化性能。实验证明该传感器可用于血样中尿酸的测定,回收率为95.0%~97.5%。The nanohybrid film of reduced graphene oxide(rGO)/Au nanoparticles(Au NPs)@polyoxometalate(P_(2)W_(18))was successfully prepared by electrodeposition of graphite oxide(GO)films supported by electrochemical reduction.The preparation process can be completed within 1 h.The prepared{PEI/rGO/Au@P2W18}electrode loaded only a monolayer catalyst exhibited good linear relationship(5.00×10^(-7)~1.50×10^(-4) mol/L),low detection limit(1.24×10^(-8) mol/L),excellent sensitivity 85.98 A/(mol·cm^(2)),and good reproducibility on detecting uric acid(UA).The enhanced catalytic performance maybe attributed to the synergistic action of rGO,P2W18 and Au NPs,especially the electron transfer during the film preparation.The sensor was used in the determination of UA in blood samples with recoveries of 95.0%~97.5%。

关 键 词：多金属氧簇 石墨烯 金纳米粒子 杂化薄膜 尿酸 

分 类 号：O646[理学—物理化学]