电感耦合等离子体质谱法和氢化物发生-原子荧光光谱法测定珍珠层粉中总砷含量的不确定度评定比较  

Comparatively Evaluating the Uncertainties of Total Arsenic in Pearl Stratum Powder That Tested byICP-MS and HG-AFS

作　　者：张铨 伍国怡 陈海钱 邵昕 梁少东 ZHANG Quan;WU Guo-Yi;CHEN Hai-Qian;SHAO Xin;LIANG Shao-Dong(Beihai Institute for Food and Drug Control,Beihai 536000,China;Beihai Municipal Government Service Center,Beihai 536000,China)

机构地区：[1]北海市食品药品检验所,广西北海536000 [2]北海市政务服务中心,北海536000

出　　处：《中国药物经济学》2023年第5期97-101,共5页China Journal of Pharmaceutical Economics

基　　金：广西壮族自治区市场监督管理局自筹经费科技项目(GSJKJZ2022-4)。

摘　　要：目的采用电感耦合等离子体质谱法(ICP-MS)和氢化物发生-原子荧光光谱法(HG-AFS)分别测定珍珠层粉中总砷含量,并对测量结果进行不确定度评定比较。方法根据《测量不确定度评定与表示》,对ICP-MS和HG-AFS测定珍珠层粉中总砷含量的不确定度分量进行分析,并进行不确定度评定。结果称样量为0.5 g时,ICP-MS测定结果为(0.96±0.11)mg/kg,HG-AFS测定结果为(0.98±0.14)mg/kg,包含因子k=2。结论用ICP-MS和HG-AFS测定珍珠层粉中总砷含量,ICP-MS不确定度低于HG-AFS。Objective The total content of arsenic in pearl stratum powder was respectively determined by inductively coupled plasma mass spectrometry(ICP-MS)and hydride Generation-Atomic Fluorescence Spectrometry(HG-AFS),and the uncertainties of the testing results were evaluated and compared.Methods According to Evaluation and Expression of Uncertainty in Measurement,the uncertainties were evaluated through analyzing the uncertainty components of testing the total content of arsenic in pearl stratum powder by ICP-MS and HG-AFS.Results The determination results of arsenic were(0.96±0.11)mg/kg by ICP-MS and(0.98±0.14)mg/kg by HG-AFS(coverage factor:k=2)respectively,when the weigh of test sample was 0.5 g.Conclusion The results suggested that ICP-MS was more advanced and precise than HG-AFS on the arsenic content testing of Pinctada martensi.

关 键 词：电感耦合等离子体质谱法 氢化物发生-原子荧光光谱法 砷 不确定度 

分 类 号：R282.5[医药卫生—中药学]