胆石症与胆囊切除术后患者的胃排空情况:超声法测定  

Gastric emptying in patients with cholelithiasis and in patients following cholecystectomy:measurement by ultrasonography

作　　者：吴可汀 高巨[1] 沈徳娟 穆子涵 辛超 葛亚丽[1] Wu Keting;Gao Ju;Shen Dejuan;Mu Zihan;Xin Chao;Ge Yali(Department of Anesthesiology,Northern Jiangsu People′s Hospital,Yangzhou 225000,China;Department of Ultrasound,Northern Jiangsu People′s Hospital,Yangzhou 225000,China)

机构地区：[1]江苏省苏北人民医院麻醉科,扬州225000 [2]江苏省苏北人民医院超声科,扬州225000

出　　处：《中华麻醉学杂志》2023年第4期406-409,共4页Chinese Journal of Anesthesiology

基　　金：江苏省青年医学重点人才项目(QNRC2016337)。

摘　　要：目的通过超声法测定,评价胆石症与胆囊切除术后患者的胃排空情况。方法选择胆石症与胆囊切除术后患者各30例,健康志愿者30名,性别不限,年龄18~64岁,BMI 18~30 kg/m^(2),ASA分级Ⅰ或Ⅱ级,分别记为胆石症组(CH组)、胆囊切除术后组(PC组)和健康志愿者组(HV组),评估入组对象近3个月消化不良评分;于空腹状态下服用半固体测试餐(300 kcal),于空腹(T_(0))、服用测试餐后5、15、30、45、60、90和120 min(T_(1~7))时采用超声仪测定胃窦横截面积(CSA),计算T_(5,6)时胃排空分数,计算胃半排空时间、服用测试餐后120 min时胃窦剩余面积。结果与HV组比较,CH组和PC组近3个月消化不良评分升高,T_(3~7)时CSA增加,T_(5,6)时胃排空分数降低,胃半排空时间延长,T_(7)时胃窦剩余面积增加(P<0.05);与CH组比较,PC组T_(4~7)时CSA增加,T_(5,6)时胃排空分数降低,胃半排空时间延长,T_(7)时胃窦剩余面积增加(P<0.05)。结论相较健康志愿者,胆石症与胆囊切除术后患者胃排空时间较长,胆囊切除术后患者更长。Objective To evaluate the gastric emptying in the patients with cholelithiasis and in the patients following cholecystectomy by ultrasonography.Methods Thirty patients with cholelithiasis,30 post-cholecystectomy patients and 30 healthy volunteers,of either sex,aged 18-64 yr,with body mass index of 18-30 kg/m^(2),of American Society of Anesthesiologists Physical Status classificationⅠorⅡ,were selected and divided into cholelithiasis group(group CH),post-cholecystectomy group(group PC)and healthy volunteer group(group HV).The indigestion scores of the enrolled subjects in the past 3 months were assessed;the subjects took a semi-solid test meal(300 kcal)in the fasting state,and the cross-sectional area(CSA)of the gastric sinus was measured using ultrasound at fasting(T0)and 5,15,30,45,60,90 and 120 min after the test meal was taken(T_(1-7)).The gastric emptying fraction at T_(5,6)was calculated.The gastric half-emptying time and remaining area of the gastric sinus at T_(7)were also calculated.Results Compared with group HV,dyspepsia scores were significantly increased within the past 3 months(P<0.05),the CSA of the gastric sinus was increased at T_(3-7),the gastric emptying fraction was decreased at T5-6,the gastric half-emptying time was prolonged,and the remaining area of the gastric sinus was increased at T_(7)in group CH and group PC(P<0.05).Compared with group CH,the CSA of the gastric sinus was significantly increased at T_(4-7),the gastric emptying fraction was decreased at T_(5,6),the gastric half-emptying time was prolonged,and the remaining area of the gastric sinus was increased at T_(7)in group PC(P<0.05).Conclusions Gastric emptying time is longer in the patients with cholelithiasis and in the patients following cholecystectomy than in healthy subjects and is further prolonged after cholecystectomy in the patients.

关 键 词：胆石症 胆囊切除术 胃排空 健康受试者 

分 类 号：R614[医药卫生—麻醉学]