中药当归的药理作用及机制研究进展  

Research progress on pharmacological effect and mechanism of Chinese medicine Angelica sinensis

作　　者：郭双岩 梁旗 吕洁丽[1] 张来宾[1] GUO Shuangyan;LIANG Qi;LYU Jieli;ZHANG Laibin(School of Pharmacy,Xinxiang Medical University,Xinxiang 453003,Henan Province,China)

机构地区：[1]新乡医学院药学院,河南新乡453003

出　　处：《新乡医学院学报》2023年第7期678-685,共8页Journal of Xinxiang Medical University

基　　金：国家自然科学基金资助项目(编号:81773898);河南省优秀青年科学基金项目(编号:212300410066)。

摘　　要：中药当归来源于伞形科植物当归Angelica sinensis(Olive.)Diels的干燥根,是中医临床常用的大宗药材之一,具有补血活血、调经止痛、润肠通便的功效,可用于治疗血虚萎黄、眩晕心悸、月经不调、经闭痛经及肠燥便秘等。中药当归具有促进造血、抗凝血、降血压、抗炎镇痛、抗氧化、抗肿瘤、保肝护肾等药理作用。本文对中药当归的药理作用及机制进行综述,以期为当归的资源开发和临床应用提供参考。Chinese medicine Angelica sinensis is derived from the dried roots of the umbelliferae plant Angelica sinensis(Olive.)Diels,which is one of the most commonly used Chinese medicines in clinical practice.Angelica sinensis has the effects of nourishing blood and promoting blood circulation,regulating menstruation and relieving pain,and moistening the bowel to relieve constipation;and it can be used to treat blood deficiency and malnutrition,dizziness and palpitation,irregular menstruation,amenorrhea and intestinal dryness with constipation.Angelica sinensis has pharmacological effects such as promoting hematopoiesis,anticoagulation,decreasing blood pressure,anti-inflammation and analgesia,anti-oxidation,anti-tumor,protecting liver and kidney etc.This article reviews the pharmacological effects and mechanisms of traditional Chinese medicine Angelica sinensis,in order to provide reference for the resource development and clinical application of Angelica sinensis.

关 键 词：当归 药理作用 中药 

分 类 号：R285[医药卫生—中药学]