新型水凝胶止血材料的研究进展  

Research progress of new hydrogel hemostatic materials

作　　者：龚佳俊 宋慧 李佩炫 王建南[1,2] GONG Jiajun;SONG Hui;LI Peixuan;WANG Jiannan(College of Textile and Clothing Engineering,Soochow University,Suzhou 215021,China;Key Laboratory of Textile Industry for Silk Products in Medical and Health Use,Suzhou 215123,China)

机构地区：[1]苏州大学纺织与服装工程学院,江苏苏州215021 [2]苏州大学纺织行业医疗健康用蚕丝制品重点实验室,江苏苏州215127

出　　处：《功能材料》2023年第6期6088-6094,6102,共8页Journal of Functional Materials

基　　金：国家自然科学基金项目(51873141)。

摘　　要：伤口的快速止血和愈合对于治疗意外事故出血具有重要意义。水凝胶作为一类极为亲水的多维网络结构凝胶,以其出色的流变性、粘附性和可注射性在止血材料方面极具应用优势,尤其在不规则创面和较深层伤口处有着其它形态材料不可替代的止血效果。天然多糖聚合物、蛋白质及合成类高分子聚合物等水凝胶因具备高吸水性、生物相容性、血细胞黏附性或激活凝血因子等功能在止血材料领域的应用受到广泛的关注,同时取得了较大的研究进展。对近年来各种水凝胶止血材料的制备和最新的应用研究成果进行全面综述,并对水凝胶止血材料的发展前景进行展望。The rapid hemostasis and healing of wounds is of great significance for the treatment of accidental bleeding.As a kind of extremely hydrophilic multi-dimensional network structure gel,hydrogel has great application advantages in hemostatic materials due to its excellent rheology,adhesion and injectability,especially in irregular wounds and deeper wounds.It has an irreplaceable hemostatic effect of other shape materials.Hydrogels such as natural polysaccharide polymers,proteins and synthetic macromolecular polymers have attracted extensive attention due to their high water absorption,biocompatibility,adhesion of blood cell,or activation of coagulation factors in the field of hemostatic materials,and have made great progress in research.In this paper,the preparation of various hydrogel hemostatic materials and the latest application research achievements in recent years are comprehensively reviewed,and the development prospects of hydrogel hemostatic materials are prospected.

关 键 词：水凝胶 多糖 蛋白质 止血性能 伤口止血 

分 类 号：TS101.4[轻工技术与工程—纺织工程]