甘肃3种中草药加工副产物中关键药效成分含量分析  

Content analysis of the key pharmacodynamic components in the by-products of three Chinese herbal medicines in Gansu province

作　　者：王娜 黎天 尤宏争[3] 毕相东[1] 戴伟[1] 阮威霖 陈云 丁子草 WANG Na;LI Tian;YOU Hongzheng;BI Xiangdong;DAI Wei;RUAN Weilin;CHEN Yun;DING Zicao(Tianjin Key Laboratory of Aqua-Ecology and Aquaculture,Tianjin Agricultural University,Tianjin 300384,China;Agricultural Technology Extension Station of Gannan Tibetan Autonomous Prefecture,Hezuo,Gansu Province 747000,China;Tianjin Fisheries Research Institute,Tianjin 300384,China;Zhuoni County Jiufeng Ecological Pharmaceutical Co.,LTD,Zhuoni,Gansu Province 747600,China)

机构地区：[1]天津农学院天津市水产生态及养殖重点实验室,天津300384 [2]甘肃省甘南藏族自治州农业技术推广站,甘肃合作747000 [3]天津市水产研究所,天津300384 [4]卓尼县九峰生态药业有限责任公司,甘肃卓尼747600

出　　处：《中国饲料》2023年第12期76-80,共5页China Feed

基　　金：甘肃省科技计划项目民生科技专项(21CX6NP223);天津市自然科学基金面上项目(22JCYBJC00430);天津市科技援助项目(22ZYCGSN00050);国家自然科学基金面上项目(No.32172978)。

摘　　要：目前,无抗养殖已成为水产养殖业的必然发展趋势,中草药被认为是抗生素的最佳替代品。本研究采用高效液相色谱技术对甘肃地区3种中草药加工副产物(大黄边角料、当归侧根和党参杆)中关键药效成分含量进行测定,分析其作为水产饲料添加剂的可行性。研究结果表明,大黄边角料、当归侧根和党参杆中浸出物含量均可达到2020年版《中国药典》中的标准。大黄边角料中游离蒽醌含量(0.630%)明显高于大黄中游离蒽醌含量(0.288%)。当归和当归侧根中阿魏酸含量相差不大,分别为0.113%和0.118%。党参杆中党参炔苷含量为0.178%,略低于党参中党参炔苷含量(0.193%)。Antibiotic-free farming has become an inevitable trend in the development of aquaculture.Chinese herbal medicine is considered to be the best substitute for antibiotics.In this study,high-performance liquid chromatography was used to determine the contents of the key pharmacodynamic components in the by-products of three authentic Chinese herbal medicines(Rhubarb scrap,Angelica lateral root and Codonopsis stem)in Gansu Province,and the feasibility of using them as aquatic feed additives was analyzed.The results showed that the contents of extracts in above three by-products could reach the standards in the 2020 edition of Chinese Pharmacopoeia.The content of free anthraquinone in Rhubarb scrap(0.630%)was significantly higher than that in Rhubarb(0.630%).The ferulic acid content of Angelica and Angelica lateral root was 0.113%and 0.118%,respectively.The content of lobetyolin in Codonopsis stem was 0.178%,which was slightly lower than that in Codonopsis(0.193%).

关 键 词：中草药加工副产物 关键药效成分 无抗养殖 水产饲料添加剂 

分 类 号：S816.7[农业科学—饲料科学]