二次肺移植手术方式与预后分析:单中心经验  

Surgical methods and prognosis of lung retransplantation:A single center review

作　　者：张云翔 王梓涛 赵晋 陈静瑜[1] Zhang Yunxiang;Wang Zitao;Zhao Jin;Chen Jingyu(Wuxi People's Hospital Affiliated to Nanjing Medical University Lung transplantation center,Wuxi 214000,Jiangsu,China)

机构地区：[1]南京医科大学附属无锡市人民医院肺移植中心,江苏无锡214000

出　　处：《实用器官移植电子杂志》2023年第3期219-224,共6页Practical Journal of Organ Transplantation(Electronic Version)

摘　　要：目的 探讨二次肺移植手术方式选择及其对预后的影响。方法 回顾性分析南京医科大学附属无锡市人民医院肺移植中心自2015年1月1日至2021年12月31日期间因慢性移植功能障碍(chronic lung allograft dysfunction, CLAD)而进行二次肺移植的患者共15例。本文对二次移植适应证、术中情况、围术期及远期生存率进行分析,并根据手术方式选择进行组内比较。结果 15例CLAD患者中,右单肺及双肺移植生存率优于左单肺移植,且双肺移植预后不优于右单肺移植。结论 二次肺移植的受者的手术方式可能影响患者的预后。根据患者适应证的具体情况合理的手术方式需进一步探索。Objective To explore the effect of surgical method selection on prognosis of lung re-transplantation.Methods A retrospective cohort study was conducted on patients(n=15)who chose re-transplantation due to chronic lung allograft dysfunction(CLAD)at Wuxi Lung Transplant Center from January 1,2015 to December 31,2021.We analyzed the indications for re-transplantation,intraoperative conditions,perioperative and long-term survival rates,and compared them within groups based on the choice of surgical methods.Results In the 15 CLAD patients,the survival rate of patients who chose right single lung and double lung re-transplantation was better than that of left single lung re-transplantation,while double lung re-transplantation was not better than right single lung transplantation.Conclusion The choice of surgical method for the recipient of secondary lung transplantation affects the prognosis of patients.Further exploration is needed to select reasonable surgical methods according to different indications of patients.

关 键 词：二次肺移植 慢性移植功能障碍 闭塞性细支气管炎 

分 类 号：R655.3[医药卫生—外科学]