盐酸赛庚啶片的近红外光谱快速鉴别方法研究  

A Method for Qualitative and Rapid Identification of Cyproheptadine Hydrochloride Tablets by NIR Spectra

作　　者：苗爱东 雷虹 刘海英 MIAO Ai-dong;LEI Hong;LIU Hai-ying(Office for Drug and Instrument Supervision and Inspection,Zhengzhou Joint Logistic Support Center,Beijing 100071,China)

机构地区：[1]郑州联勤保障中心药品仪器监督检验站,北京100071

出　　处：《解放军药学学报》2023年第3期195-198,共4页Pharmaceutical Journal of Chinese People's Liberation Army

摘　　要：目的建立盐酸赛庚啶片的近红外光谱快速鉴别方法。方法收集12个不同厂家生产的82批次盐酸赛庚啶片,采集其近红外光谱,建立了盐酸赛庚啶片的快速鉴别方法。结果所建立的快速鉴别方法可以较好地鉴别盐酸赛庚啶片,方法快速、准确、无损并且绿色环保。结论建立的盐酸赛庚啶片的近红外光谱分析方法可广泛应用于基层单位药品的快速鉴别。Objective To establish a rapid identification method for cyproheptadine hydrochloride tablets with near-infrared(NIR)spectra.Methods Eighty-two batches of cyproheptadine hydrochloride tablets from twelve manufacturers were collected,and their NIR spectra were used to establish a rapid identification method for cyproheptadine hydrochloride tablets.Results The established method for rapid identification could clearly distinguish the samples of cyproheptadine hydrochloride tablets from other drugs.This method proved to be rapid,accurate,non-destructive and environmentally friendly.Conclusion The established qualitative method can be applied to rapid drug determination in grass-roots institutions.

关 键 词：近红外光谱 盐酸赛庚啶片 药品快速鉴别 

分 类 号：R917[医药卫生—药物分析学]