^(99m)Tc⁃MDP SPECT/CT显像在盆腔肿瘤放疗后骨盆功能不全骨折诊断中的应用  

^(99m)Tc⁃MDP SPECT/CT Imaging in the Diagnosis of Pelvic Insufficiency Fracture After Radiotherapy for Pelvic Neoplasms

作　　者：严肃 杨建忠 周程敏 程鹏 YAN Su;YANG Jianzhong;ZHOU Chengmin;CHENG Peng(Medical Image Center,Yixing Hospital,Jiangsu University)

机构地区：[1]江苏大学附属宜兴医院影像中心

出　　处：《中国医学计算机成像杂志》2023年第3期316-320,共5页Chinese Computed Medical Imaging

摘　　要：目的:探讨^(99m)Tc⁃MDP全身骨显像联合骨盆SPECT/CT融合显像在盆腔肿瘤放疗后骨盆功能不全骨折(PIF)诊断中的价值。方法:回顾性分析50例盆腔肿瘤放疗后CT及SPECT/CT检查疑似PIF患者的临床及影像资料,结合穿刺活检及影像随访确定诊断,分析总结PIF的CT和SPECT/CT影像特征,比较2种检查方法诊断PIF的差异。结果:20例患者确诊为PIF,其中CT检出12例,SPECT/CT检出19例;二者诊断PIF的灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为60.0%(12/20)、93.3%(28/30)、80.0%(40/50)、85.7%(12/14)、77.8%(28/36)和95%(19/20)、90.0%(27/30)、92.0%(46/50)、86.4%(19/22)、96.4%(27/28),2种方法诊断PIF的差异具有统计学意义(χ^(2)=24.253,P<0.001)。结论:与CT相比,全身骨显像联合骨盆SPECT/CT融合显像对PIF具有更好的诊断效能。Purpose:To investigate the value of^(99m)Tc-MDP whole-body bone imaging combined with pelvic SPECT/CT fusion imaging in the diagnosis of pelvic insufficiency fracture(PIF)after radiotherapy for pelvic neoplasms.Methods:The imaging and clinical data of 50 patients with suspected PIF who underwent CT and SPECT/CT examination after radiotherapy for pelvic neoplasms were retrospectively analyzed.Diagnosis was determined by needle biopsy or imaging follow-up.The CT and SPECT/CT imaging characteristics of PIF were analyzed,and the differences of the two methods in diagnosing PIF were compared.Results:Twenty patients were finally diagnosed with PIF,including 12 cases detected by CT and 19 cases detected by SPECT/CT.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of the two methods for the diagnosis of PIF were 60.0%(12/20),93.3%(28/30),80.0%(40/50),85.7%(12/14),77.8%(28/36)and 95%(19/20),90.0%(27/30),92.0%(46/50),86.4%(19/22),96.4%(27/28),respectively.The differences between the two methods in diagnosing PIF were with statistical significance(χ^(2)=24.253,P<0.001).Conclusions:The whole-body bone imaging combined with pelvic SPECT/CT fusion imaging has better diagnostic ability for PIF than CT.

关 键 词：骨盆功能不全骨折 盆腔肿瘤 单光子发射计算机体层摄影 计算机体层成像 ^(99m)Tc⁃亚甲基二膦酸盐 

分 类 号：R445.5[医药卫生—影像医学与核医学]