The rat eustachian tube:Anatomical, histological, and radiological features  

作　　者：Zhe Wang Hong-Tao Hu Nader Bakheet Sung Hwan Yoon Jung-Hoon Park Kun Yung Kim Jae Yong Jeon Woo Seok Kang Ye Ree Kim Jorge E.Lopera Hong Ju Park Ho-Young Song 

机构地区：[1]Department of Radiology and Research Institute of Radiology,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea [2]Department of Rehabilitation Medicine,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea [3]Department of Otorhinolaryngology Head&Neck Surgery,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea [4]Biomedical Engineering Research Center,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea [5]Department of Radiology,Tianjin Medical University General Hospital,Anshan Road 154,Heping District,CN,300052,China [6]Department of Minimal-Invasive Intervention,Affiliated Cancer Hospital of Zhengzhou University,127 Dongming Road,Zhengzhou City,Henan Province,450003,China [7]Gastrointestinal Endoscopy and Liver Unit,Kasr Al-Ainy Faculty of Medicine,Cairo University,Cairo,Egypt [8]Department of Radiology,Biomedical Research Institute of Chonbuk National University Hospital,Jeonju-si,Jeollabuk-do,Republic of Korea [9]Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital,Jeonju-si,Jeollabuk-do,Republic of Korea [10]Department of Radiology,UT Health Science Center at San Antonio,7703 Floyd Curl Drive,San Antonio,TX,78229,USA

出　　处：《Journal of Interventional Medicine》2023年第1期14-19,共6页介入医学杂志（英文）

基　　金：funding from the Korea Health Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (HI17C0881)。

摘　　要：Purpose: This study investigated the anatomical and histological characteristics of the rat Eustachian tube(E-tube)and the feasibility of Eustachian tubography in a rat model.Materials and methods: Fifteen male Wistar rats were used in this study, and the bilateral E-tubes of each rat were examined. Ten E-tubes were used for anatomical studies, another ten for histological analysis, and the other ten for Eustachian tubography. Five rats were euthanized and decapitated, and ten E-tubes were dissected to describe the anatomy of the E-tube. Ten E-tube specimens obtained from five other rats were sectioned to investigate Etube histology. Eustachian tubography was performed on the bilateral E-tubes of the other five rats using the trans-tympanic approach.Results: The rat E-tubes consisted of bony and membranous parts. Cartilage and bone tissue covered only the bony part. The E-tubes’ mean diameter and overall length were 2.97 mm and 4.96 mm, respectively. The tympanic orifices’ mean diameter was 1.21 mm. The epithelium of E-tubes was mainly composed of pseudostratified ciliated and goblet cells. Eustachian tubography was successfully performed on both sides of the E-tube for each rat.The technical success rate was 100%, the average running time was 4.9 min, and no procedure-related complications occurred. On tubography images, the E-tube, tympanic cavity, and nasopharynx could be identified because of the visualization of bony landmarks.Conclusion: In this study, we described the anatomical and histological features of rat E-tubes. With the aid of these findings, E-tube angiography was successfully performed using a transtympanic approach. These results will facilitate further investigation of E-tube dysfunction.

关 键 词：Rats Eustachian tube ANATOMY HISTOLOGY RADIOGRAPHY 

分 类 号：R764.29[医药卫生—耳鼻咽喉科] R322.92[医药卫生—临床医学]