Brain asymmetry: a novel perspective on hemispheric network  

作　　者：Bin Wang Lan Yang Wenjie Yan Weichao An Jie Xiang Dandan Li 

机构地区：[1]College of Computer Science and Technology,Taiyuan University of Technology,Jinzhong 030600,Shanxi,China [2]Graduate School of Interdisciplinary Science and Engineering in Health Systems,Okayama University,Okayama,Japan

出　　处：《Brain Science Advances》2023年第2期56-77,共22页神经科学（英文）

基　　金：This work was supported by the National Natural Science Foundation of China(Grant Nos.62176177,61906130);the National Key R&D Program of China(Grant No.2018AAA0102604);the Natural Science Foundation of Shanxi(Grant No.20210302123112);the Research Project Supported by Shanxi Scholarship Council of China(Grant No.2021-039).

摘　　要：Brain asymmetry,involving structural and functional differencesbetween the two hemispheres,is a major organizational principle ofthe human brain.The structural and functional connectivity withineach hemisphere defines the hemispheric network or connectome.Elucidating left-right differences of the hemispheric network providesopportunities for brain asymmetry exploration.This review examinesthe asymmetry in the hemispheric white matter and functionalnetwork to assess health and brain disorders.In this article,the brain asymmetry in structural and functional connectivity includingnetwork topologies of healthy individuals,involving brain cognitivesystems and the development trend,is highlighted.Moreover,theabnormal asymmetry of the hemispheric network related to cognition changes in brain disorders,such as Alzheimer’s disease,schizophrenia,autism spectrum disorder,attention deficit hyperactivity disorder,and bipolar disorder,is presented.This review suggests that thehemispheric network is highly conserved for measuring human brain asymmetries and has potential in the study of the cognitivesystem and brain disorders.

关 键 词：hemispheric network brain asymmetry graph theory cognition system brain disorders 

分 类 号：R322.8[医药卫生—人体解剖和组织胚胎学]