鼻腔成釉细胞瘤1例及文献分析  

Nasal ameloblastoma:a case report and literature analysis

作　　者：李笑颖 李岩[2] 吴允刚[3] 张辉[3] 马林祥[3] 赵玉凤[3] 孙聚兴[3] 张瑾 LI Xiaoying;LI Yan;WU Yungang;ZHANG Hui;MA Linxiang;ZHAO Yufeng;SUN Juxing;ZHANG Jin(School of Clinical Medicine,Jining Medical University,Jining 272000,Shandong,China;Department of Pathology,Affiliated Hospital of Jining Medical University,Jining 272000,Shandong,China;Department of Otorhinolaryngology&Head and Neck Surgery,Affiliated Hospital of Jining Medical College,Jining 272000,Shandong,China)

机构地区：[1]济宁医学院临床医学院,山东济宁272000 [2]济宁医学院附属医院病理科,山东济宁272000 [3]济宁医学院附属医院耳鼻咽喉头颈外科,山东济宁272000

出　　处：《山东大学耳鼻喉眼学报》2023年第3期30-34,共5页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：济宁市科技计划重点研发计划项目(2021YXNS028,2021YXNS048,2021YXNS052)。

摘　　要：目的探讨鼻腔成釉细胞瘤的临床特点及治疗方法,以便于早发现早诊断。方法回顾性分析1例鼻腔成釉细胞瘤患者的临床资料并复习相关文献。结果成釉细胞瘤多发生于口腔及颌骨,发生于鼻腔鼻窦极其少见。患者可表现为鼻塞、鼻出血、鼻窦区压痛等,病情严重者可导致面部畸形。影像学检查可确定病变的范围及邻近组织关系。治疗主要采取手术彻底清除病变,可联合靶向治疗综合治疗。术后复发率高,可恶变为成釉细胞癌。结论鼻腔成釉细胞瘤极其罕见,虽为良性肿瘤,但是其生物学行为具有侵袭性。患者的临床表现及影像学检查不具有特异性,需要通过病理学检查确诊。Objective To investigate the clinical characteristics and treatment of nasal ameloblastoma for its early detection and diagnosis.Methods The clinical data of one patient with nasal ameloblastoma were retrospectively analyzed and the related literatures were reviewed.Results Ameloblastoma occurred frequently in the oral cavity and jaw but rarely in the nasal cavity and sinus.Patients can present with nasal congestion and bleeding,tenderness in the sinus area,decreased vision,etc.,and in severe cases,facial deformity can be caused.Imaging can determine the extent of the lesion and the relationship between adjacent tissues.The main treatment is complete removal of the lesion by surgery,combined with targeted therapy for comprehensive treatment.The postoperative recurrence rate is high,and ameloblastic carcinoma transformation is common.Conclusion Ameloblastoma of the nasal cavity is a rare and benign tumor but its biological behavior is invasive.The clinical manifestations and imaging examinations of patients are not specific and need to be confirmed by pathological biopsy.

关 键 词：成釉细胞瘤 肿瘤 鼻腔 鼻窦 功能性内窥镜鼻窦手术 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]