睾丸和附睾缺氧导致精液质量下降的研究进展  

Research progress of declined semen quality caused by hypoxia in testis and epididymis

作　　者：宋阳阳 郑洁 陈竹 Song Yangyang;Zheng Jie;Chen Zhu(Health Science Center,Yangtze University,Jingzhou 434023,China;Department of Reproduction,Maternal and Child Health Hospital of Hubei Province,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430070,China)

机构地区：[1]长江大学医学部,荆州434023 [2]华中科技大学同济医学院附属湖北省妇幼保健院生殖中心,武汉430070

出　　处：《中华生殖与避孕杂志》2023年第5期535-540,共6页Chinese Journal of Reproduction and Contraception

基　　金：国家自然科学基金(31701074)。

摘　　要：近年来,男性精液质量逐年下降,影响着全球数以百万的育龄期人群,越来越多的学者开始关注影响精液质量的因素。大量研究证实,睾丸和附睾缺氧会导致精子数量减少、精子活力下降,而精子数量和活力的异常与精子细胞的过度凋亡、生殖内分泌紊乱、机体内活性氧水平过高等密切相关。本文就睾丸和附睾组织缺氧对精液质量的影响及其作用机制进行综述,以期为从事相关研究和临床服务的专业人员提供有益的参考。In recent years,the quality of male semen has been declining year by year,affecting millions of people of childbearing potential worldwide.So more and more scholars are paying attention to the factors affecting the quality of semen.Numerous studies have suggested that hypoxia in testis and epididymis could result in decreased number and activity of sperms,which are closely associated with excessive apoptosis of sperm cells,reproductive-endocrine disorders,and excessively high reactive oxygen species in the bodies.This paper reviewed the effects of hypoxia in testis and epididymis on semen quality and its mechanism of action,in an effort to provide useful evidence for the researchers and healthcare practitioners.

关 键 词：缺氧 精液质量 精子发生 精子成熟 

分 类 号：R697.22[医药卫生—泌尿科学]