2006年至2020年抗苗勒管激素相关研究趋势及热点分析  

Research trends and hotspots of anti-Müllerian hormone from 2006 to 2020

作　　者：杜超 范馨月 侯开波 关小川 王博伦 高艳 于月新 Du Chao;Fan Xinyue;Hou Kaibo;Guan Xiaochuan;Wang Bolun;Gao Yan;Yu Yuexin(Department of Reproductive Medicine,General Hospital of Northern Theater Command,Shenyang 110016,China;Student Affairs Department,Shengjing Hospital Affiliated to China Medical University,Shenyang 110004,China)

机构地区：[1]北部战区总医院生殖医学科,沈阳110016 [2]中国医科大学附属盛京医院学生工作部,沈阳110004

出　　处：《中华生殖与避孕杂志》2023年第5期541-547,共7页Chinese Journal of Reproduction and Contraception

基　　金：辽宁省科学技术计划课题(2020JH2/10300118);军委后勤保障部重点项目(16JS014)。

摘　　要：目的分析2006年至2020年抗苗勒管激素相关研究趋势及热点,为今后相关领域研究提供借鉴与参考。方法基于PubMed数据库,检索2006年1月1日至2020年12月31日收录的抗苗勒管激素相关文献,采用文献计量学方法,以每5年为时间节点,分析每个阶段与抗苗勒管激素相关的发文趋势、高频主题词/副主题词共现和研究热点,对其发展趋势进行探讨和预测。结果本文共检索到相关文献4276篇,总发文量呈增长趋势。相关研究热点逐步增多,2005年至2010年的核心研究热点为抗苗勒管激素的生物标志物作用;2011年至2015年、2016年至2020年两个阶段的核心研究热点均为抗苗勒管激素与多囊卵巢综合征。结论抗苗勒管激素相关研究热点不断拓展与丰富的同时,也存在一定更迭和交替,部分新兴热点仍具有进一步研究的价值和意义。抗苗勒管激素Ⅱ型受体与生育力保存可能成为今后该领域的新兴热点。Objective To analyze the research trends and hotspots of anti-Müllerian hormones(AMH)from 2006 to 2020,and to provide reference for future research in related fields.Methods Based on the PubMed database,the literatures related to AMH collected from January 1st,2006 to December 31st,2020 were retrieved,and the bibliometric method was used to analyze the relationship between each stage and AMH with every 5 years as the time node.The publication trends,high-frequency main MeSH/subheadings co-occurrence and research hotspots related to AMH were discussed and forecasted.Results A total of 4276 related literatures were retrieved in this paper,and the total number of published papers showed an increasing trend.Relevant research hotspots were gradually increasing.The core research from 2005 to 2010 was the biomarker effect of AMH;from 2011 to 2015 and 2016 to 2020,the core research hotspots were all AMH and polycystic ovary syndrome.Conclusion While the research hotspots related to AMH have been continuously expanded and enriched,there are also certain changes and alternations,and some emerging hotspots still have the value and significance of further research.AMH typeⅡreceptor and fertility preservation may become an emerging hotspot in this field in the future.

关 键 词：抗苗勒管激素 多囊卵巢综合征 卵巢反应性 生育力保存 

分 类 号：G353.1[文化科学—情报学] R711.75[医药卫生—妇产科学]