Intergenerational hyperglycemia through epigenetic alterations of gametes  

作　　者：Fei Mao Xiaoying Li 

机构地区：[1]Ministry of Education Key Laboratory of Metabolism and Molecular Medicine,Department of Endocrinology and Metabolism,Zhongshan Hospital,Fudan University,Shanghai 200032,China [2]Shanghai Key Laboratory of Metabolic Remodeling and Health,Institute of Metabolism and Integrative Biology,Fudan University,Shanghai 200438,China

出　　处：《Life Metabolism》2022年第2期107-108,共2页生命（代谢（英文）

摘　　要：In a recent study published in Nature,Chen et al.reported a mechanism through which hyperglycemia is transmitted from female mice to their offspring through their eggs and DNA methylation of the paternal-derived pancreatic Gck promoter is increased due to a decrease of maternal effector TET3 dioxygenase.

关 键 词：alterations FEMALE 

分 类 号：R587.1[医药卫生—内分泌]