肠易激综合征临床评估与住院期间直接经济负担指标的典型相关分析  

Typical correlation analysis between clinical evaluation of irritable bowel syndrome and direct economic burden indicators during hospitalization

作　　者：莫嘉浩 刘畅[1] 樊珑秀 陈立基 钟彩玲[2] 吴少华 郑婕 张北平[2] MO Jiahao;LIU Chang;FAN Longxiu;CHEN Liji;ZHONG Cailing;WU Shaohua;ZHENG Jie;ZHANG Beiping(Guangzhou University of Chinese Medicine,Guangzhou,510405,China;Department of Spleen and Stomach Diseases,Guangdong Provincial Hospital of Traditional Chinese Medicine)

机构地区：[1]广州中医药大学,广州510405 [2]广东省中医院脾胃病科

出　　处：《中国中西医结合消化杂志》2023年第6期434-438,共5页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：广东省教育厅高校科研项目-重点领域项目(No:2021ZDZX2059);广州中医药大学“双一流”与高水平大学学科协同创新团队(No:2021xk58);广东省科技创新战略专项(No:pdjh2021b0123);广州市校院联合资助项目(No:202201020377)。

摘　　要：目的:探讨肠易激综合征患者临床评估指标与住院期间直接经济负担指标之间的相关性。方法:回顾广东省中医院2010年1月—2022年12月收治的271例肠易激综合征患者的病历资料,观察临床评估指标(年龄、病程、合并病情况、血清白蛋白计量、血红蛋白计量、入院肠道症状、入院上消化道症状、全身症状等)与住院期间直接经济负担指标(住院时间和住院费用),对两组资料进行典型相关分析。结果:肠易激综合征患者入院中医证型以脾虚湿盛证为主,老年人证型中虚证较其他年龄层明显增加。典型相关分析结果提示,纳入肠道症状评分后的第1典型相关系数为0.615(P<0.001)。年龄、病程、合并病种数、肠道症状评分与住院时间、费用均呈正相关(P<0.05);血清白蛋白、血红蛋白与住院时间、住院费用呈负相关(P<0.05)。结论:肠易激综合征患者的临床评估指标与经济负担指标具有一定的相关性。初诊评估肠易激综合征患者需关注患者的基础病及临床症状,还要评估患者的营养状态,从而合理用药并加强营养支持,减少患者住院经济负担。Objective To explore the correlation between the clinical evaluation indexes of irritable bowel syndrome(IBS)patients and the economic burden indexes of hospitalization.Methods The medical records of 271 patients with IBS admitted to Guangdong Provincial Hospital of Traditional Chinese Medicine from January 2010 to December 2022 were reviewed,and the clinical evaluation indexes(age,course of disease,comorbidities,serum albumin measurement,hemoglobin measurement,admission intestinal symptoms,admission upper digestive tract symptoms,systemic symptoms,etc.)and the economic burden index of hospitalization(hospitalization time and hospitalization expenses)were observed,and the typical correlation analysis was performed on the two groups of data.Results Patients with IBS admitted to the hospital are mainly characterized by spleen deficiency and dampness stagnation syndrome,and the number of elderly patients with deficiency syndrome is significantly increased compared to other age groups.The results of canonical correlation analysis showed that the first canonical correlation coefficient after the intestinal symptom score was 0.615(P<0.001).Age,course of disease,number of complicated diseases,score of intestinal symptoms were positively correlated with length of stay and cost(P<0.05),while serum albumin and hemoglobin were negatively correlated with length of stay and cost of stay(P<0.05).Conclusion There is a certain correlation between the clinical evaluation index and the economic burden index of patients with IBS.In the initial diagnosis and evaluation of patients with IBS,we should pay attention to the basic disease and clinical symptoms of the patients,and also evaluate the nutritional status of the patients,so as to use drugs reasonably and strengthen nutritional support,and reduce the financial burden of the patients in hospital.

关 键 词：肠易激综合征 临床评估 经济负担 单因素相关分析 典型相关分析 

分 类 号：R256[医药卫生—中医内科学]