中西医结合诊治Cronkhite-Canada综合征1例并文献复习  

A case report of Cronkhite-Canada syndrome treated by integrated Traditional Chinese and Western Medicine and literature review

作　　者：朱虹春 许方沥 钟宇汝 和明扬 钟森[3] ZHU Hongchun;XU Fangli;ZHONG Yuru;HE Mingyang;ZHONG Sen(School of Cinical Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu,610032,China;Department of Gastroenterology,Neijiang Hospital of Traditional Chinese Medicine,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine;Department of Infectious Disease,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine)

机构地区：[1]成都中医药大学临床医学院,成都610032 [2]成都中医药大学附属医院内江中医医院消化科 [3]成都中医药大学附属医院感染科

出　　处：《中国中西医结合消化杂志》2023年第6期473-478,共6页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：成都中医药大学“杏林学者”学科人才科研提升计划(No:YYZX2020131)。

摘　　要：Cronkhite-Canada综合征(Cronkhite-Canada syndrome,CCS)一种临床罕见的非遗传性疾病,以胃肠道多发息肉和外胚层三联征为主要特征,临床症见消化道症状、皮肤色素沉着、脱发、爪甲脱落等。西医治疗CCS缺乏明确有效的治疗手段,多以经验性对症治疗为主。中医根据辨证论治,针对本例患者,辨证为脾虚夹痰热瘀毒滞肠证,治以健脾和胃、祛邪化积,先后予以口服清营汤和乌梅汤,经治疗2周后,患者好转出院。本文探讨中西医结合诊治1例CCS并文献复习,以供临床医师参考。Cronkhite-Canada syndrome(CCS)is a clinically rare nongenetic disorder that is characterized endoscopically by multiple gastrointestinal polyps and ectodermal triad.Clinical manifestations include gastrointestinal symptoms,skin pigmentation,alopecia,and nail shedding.At present,Western Medicine lacks clear and effective treatment methods for CCS,and most of them are empirical symptomatic treatment.Traditional Chinese Medicine is based on dialectical treatment for this case.The syndrome differentiation is spleen deficiency trapping phlegm,heat,stasis,and poison lingering in the intestine syndronme.The treatment is to strengthen the spleen and stomach,dispel the accumulation of evil.Oral Qingying Decoction and Wumei Decoction were given successively,after two weeks of treatment,The patient improved and was discharged.This article discusses a case of diagnosis and treatment of CCS with integrated Traditional Chinese and Western Medicine and reviews the literature for reference by clinicians.

关 键 词：CRONKHITE-CANADA综合征 胃肠道息肉 中西医治疗 病例报道 文献复习 

分 类 号：R256[医药卫生—中医内科学]