颈动脉支架置入术后发生血流动力学损害的危险因素分析  

Analysis of Risk Factors for the Occurence of Hemodynamic Damage after Carotid Artery Stenting

作　　者：邓鹏飞[1] 李递通[1] 陈锦俭[1] DENG Pengfei;LIDitong;CHEN Jinjian(Yulin Second People's Hospital,Yulin 537000,China;不详)

机构地区：[1]玉林市第二人民医院,广西玉林537000

出　　处：《中外医学研究》2023年第16期181-184,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：玉林市科学研究与技术开发计划项目(20220641)。

摘　　要：目的:分析颈动脉支架置入术(CAS)后发生血流动力学损害(HD)的危险因素。方法:回顾性选取2021年6月—2022年6月玉林市第二人民医院行CAS治疗的115例患者的资料。统计CAS后HD发生情况并进行分组,收集所有患者一般资料,统计CAS后HD发生情况,对CAS后HD发生进行单因素及多因素分析。结果:115例行CAS治疗的患者中,有31例发生HD,发生率为26.96%(31/115),纳入HD发生组。HD发生组年龄>60岁、急性脑卒中史、合并基础疾病(高脂血症、高血压、糖尿病、冠心病)、球囊后扩张、钙化斑块、重度狭窄程度、狭窄累及球部或分叉部占比均高于HD未发生组,差异有统计学意义(P<0.05)。年龄>60岁(β=1.587,OR=4.889,95%CI:1.991,12.006)、急性脑卒中史(β=1.778,OR=5.918,95%CI:2.415,14.505)、合并基础疾病[高脂血症(β=1.163,OR=3.200,95%CI:1.354,7.564)、高血压(β=1.181,OR=3.259,95%CI:1.341,7.919)、糖尿病(β=1.238,OR=3.448,95%CI:1.456,8.168)、冠心病(β=2.105,OR=8.211,95%CI:2.731,24.686)]、球囊后扩张(β=0.913,OR=2.492,95%CI:1.074,5.782)、钙化斑块(β=1.430,OR=4.179,95%CI:1.711,10.210)、重度狭窄(β=1.764,OR=5.833,95%CI:2.165,15.714)、狭窄累及球部或分叉部(β=1.573,OR=4.821,95%CI:1.548,15.017)均是CAS后HD发生的高危因素(P<0.05)。结论:CAS后HD的发生与年龄、急性脑卒中史、合并基础疾病、球囊后扩张、钙化斑块、重度狭窄、狭窄累及球部或分叉部有关。Objective:To analyze the risk factors for the occurence of hemodynamic damage(HD)after carotid artery stenting(CAS).Method:A total of 115 patients who received CAS treatment in Yulin Second People's Hospital from June 2021 to June 2022 were retrospectively selected.The occurence condition of HD after CAS was counted and they were grouped,and the general data of all patients were collected.The occurence condition of HD after CAS was counted,and the occurence of HD after CAS was analyzed by single factor and multiple factor.Result:HD occurred in 31 patients among 115 patients treated with CAS,with an incidence of 26.96%(31/115),and were included in the HD occurence group.The proportions of age>60 years old,history of acute stroke,combined with basic diseases(hyperlipidemia,hypertension,diabetes,coronary heart disease),post balloon dilatation,calcified plaque,severe stenosis degree,stenosis involving the ball or the split part in HD occurence group were higher than those in HD no occurence group,the difference was statistically significant(P<0.05).Age>60 years old(β=1.587,OR=4.889,95%CI:1.991,12.006),history of acute stroke(β=1.778,OR=5.918,95%CI:2.415,14.505),combined with basic diseases[hyperlipidemia(β=1.163,OR=3.200,95%CI:1.354,7.564),hypertension(β=1.181,OR=3.259,95%CI:1.341,7.919),diabetes(β=1.238,OR=3.448,95%CI:1.456,8.168),coronary heart disease(β=2.105,OR=8.211,95%CI:2.731,24.686)],post balloon dilatation(β=0.913,OR=2.492,95%CI:1.074,5.782),calcified plaque(β=1.430,OR=4.179,95%CI:1.711,10.210),severe stenosis(β=1.764,OR=5.833,95%CI:2.165,15.714),stenosis involving the ball or the split part(β=1.573,OR=4.821,95%CI:1.548,15.017)were high risk factors for the occurence of HD after CAS(P<0.05).Conclusion:The occurrence of HD after CAS is associated with age,history of acute stroke,combined with basic diseases,post balloon dilation,calcified plaques,severe stricture,and stenosis involving the ball or bifurcation part.

关 键 词：颈动脉支架置入术 血流动力学损害 危险因素 

分 类 号：R743[医药卫生—神经病学与精神病学]