SARS-CoV-2 shows a much earlier divergence in the world than in the Chinese mainland  

作　　者：Chaoyuan Cheng Zhibin Zhang 

机构地区：[1]State Key Laboratory of Integrated Management of Pest Insects and Rodents,Institute of Zoology,Chinese Academy of Sciences,Beijing,100101,China [2]CAS Center for Excellence in Biotic Interactions,University of Chinese Academy of Sciences,Beijing,100049,China

出　　处：《Science China(Life Sciences)》2023年第6期1440-1443,共4页中国科学（生命科学英文版）

基　　金：supported by the Ministry of Science and Technology of the People’s Republic of China (2021YFC0863400);the Institute of Zoology,Chinese Academy of Science (E0517111,E122G611)。

摘　　要：Currently,the origin and early transmission pattern of SARS-CoV-2 remain unknown.The Time to the Most Recent Common Ancestor(TMRCA)of SARS-CoV-2 has been suggested to be mid-October or November of 2019(Pekar et al.,2021;van Dorp et al.,2020)by using a small number of early samples which may not cover full lineages of its evolutionary tree.Available methods of estimating TMRCA of viruses(Drummond et al.,2003)are often time-consuming and thus constrained by using big data.

关 键 词：consuming estimating constrained 

分 类 号：R373[医药卫生—病原生物学]