肾综合征出血热患者血浆细胞因子的动态变化  

Dynamic changes of plasma cytokines in patients with hemorrhagic fever with renal syndrome

作　　者：任丹凤[1] 刘锦锋[1] 陈天艳[1] 赵英仁[1] 杨瑗[1] 何英利[1] REN Dan-feng;LIU Jin-feng;CHEN Tian-yan;ZHAO Ying-ren;YANG Yuan;HE Ying-li(Department of Infectious Diseases,First Affiliated Hospital of Xi'an Jiaotong University,Shanxi Xian 710061,China)

机构地区：[1]西安交通大学第一附属医院感染科,陕西西安710061

出　　处：《内科急危重症杂志》2023年第3期181-184,共4页Journal of Critical Care In Internal Medicine

基　　金：国家自然科学基金面上项目(No:8207032750)。

摘　　要：肾综合征出血热(HFRS)是由汉坦病毒(hantavirus)引起的以啮齿类动物为主要传染病的自然疫源性疾病,我国是HFRS的高发地区之一,其长期危害我国人民的生命健康。研究表明过度活化的免疫应答和炎症反应引起的“细胞因子风暴”是导致HFRS致病的机制之一。本文拟对HFRS患者中各种细胞因子的动态变化进行综述。Hemorrhagic fever with renal syndrome(HFRS)is a natural epidemic disease caused by Hantavirus,which mainly affects rodents.China is one of the areas with high incidence of HFRS,which endangers the life and health of Chinese people for a long time.Studies have shown that overactivated immune responses and"cytokine storms"caused by inflammatory responses are one of the mechanisms responsible for the pathogenesis of HFRS.This paper intends to review the dynamic changes of various cytokines in patients with HFRS.

关 键 词：肾综合征出血热 细胞因子 

分 类 号：R512.8[医药卫生—内科学]