不同频次针刺治疗功能性消化不良:随机对照试验  

Functional dyspepsia treated with acupuncture of different frequencies:a randomized controlled trial

作　　者：汤铠源 孙碧云 颜彦 汪汐 何欣 刘志顺[1] TANG Kai-yuan;SUN Bi-yun;YAN Yan;WANG Xi;HE Xin;LIU Zhi-shun(Department of Acupuncture and Moxibustion,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Department of TCM,Guiyang Fourth People's Hospital,Guiyang 550007,Guizhou Province;Institute of Sports Medicine,General Administration of Sport of China;School of Acupuncture-Moxibustion and Tuina,Beijing University ofCM)

机构地区：[1]中国中医科学院广安门医院针灸科,北京100053 [2]贵阳市第四人民医院中医科,贵州贵阳550007 [3]国家体育总局运动医学研究所 [4]北京中医药大学针灸推拿学院

出　　处：《中国针灸》2023年第6期622-626,共5页Chinese Acupuncture & Moxibustion

基　　金：中国中医科学院科技创新工程重大攻关项目:CI2021A03518。

摘　　要：目的:比较不同频次针刺治疗功能性消化不良(FD)患者的临床疗效。方法:将90例FD患者随机分为每周针刺3次组(31例,脱落2例)、每周针刺1次组(30例,脱落2例)及对照组(29例,脱落2例)。两个针刺组均取中脘及双侧天枢、内关、梁丘、阳陵泉、足三里和太冲,分别给予每周3次、每周1次的针刺治疗,连续治疗4周。对照组于随访结束后给予补偿性治疗。比较3组患者治疗前、治疗4周后及治疗结束后4、8周的消化不良症状(SID)积分、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分;于治疗前,治疗2、4周后及治疗结束后4、8周评定3组患者尼平消化不良生活质量指数(NDLQI)评分。结果:治疗4周后和治疗结束后4、8周,每周针刺3次组、每周针刺1次组SID积分、SAS评分、SDS评分均较治疗前降低(P<0.000 1,P<0.05)。治疗4周后,每周针刺3次组、每周针刺1次组SID积分、SAS评分、SDS评分均低于对照组(P<0.000 1);治疗2、4周后,每周针刺3次组、每周针刺1次组NDLQI评分较基线期升高值均高于对照组(P<0.05);治疗结束后4、8周,每周针刺3次组SID积分、SAS评分、SDS评分低于每周针刺1次组(P<0.001,P<0.05),NDLQI评分较基线期升高值高于每周针刺1次组(P<0.000 1)。结论:每周针刺3次改善FD患者临床症状、生活质量、情绪状态优于每周针刺1次,治疗结束后其疗效可持续8周。Objective To compare the clinical efficacy of acupuncture with different frequencies in the treatment of patients with functional dyspepsia(FD).Methods A total of 90 patients with FD were randomly divided into a 3-time acupuncture treatment per week group(3-A group,31 cases,2 cases dropped off),a 1-time acupuncture treatment per week group(1-A group,30 cases,2 cases dropped off)and a control group(29 cases,2 cases dropped off).In the two acupuncture groups,the acupoints were Zhongwan(CV 12)and bilateral Tianshu(ST 25),Neiguan(PC 6),Liangqiu(ST 34),Yanglingquan(GB 34),Zusanli(ST 36)and Taichong(LR 3),stimulated 3 times a week and once a week,respectively;and the treatment was given consecutively for 4 weeks.In the control group,no intervention was adopted,but the compensatory therapy was provided after the end of follow-up.The scores of the symptom index of dyspepsia(SID),self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were compared among the 3 groups before treatment,after 4 weeks of treatment and in 4 and 8 weeks after treatment completion separately.The score of Nepean dyspepsia life quality index(NDLQI)was evaluated before treatment,after 2 and 4 weeks of treatment and in 4 and 8 weeks after treatment completion.Results After 4 weeks of treatment and in 4 and 8 weeks after treatment completion,the scores of SID,SAS and SDS were all reduced in the 3-A group and the 1-A group when compared with the scores before treatment(P<0.0001,P<0.05).Affer 4 weeks of treatment,the scores of SID,SAS and SDS in the two acupuncture groups were lower than those in the control group(P<O.0001).After 2 and 4 weeks of treatment,the increased values of NDLQI score in the two acupuncture groups were all higher than those in the control group(P<0.05).In 4 and 8 weeks after treatment completion,the scores of SID,SAS and SDS in the 3-A group were lower than those in the 1-A group(P<0.001,P<0.05),and the increased values of NDLQI score in the 3-A group were higher than those in the 1-A group(P<0.0001).Conclusion Acupun

关 键 词：功能性消化不良 针刺 针刺频次 随机对照试验 

分 类 号：R246.1[医药卫生—针灸推拿学]