新加汤合当归四逆汤加味治疗慢性萎缩性胃炎脾胃虚寒证的效果  

Effect of Xinjia Decoction combined with Danggui Sini Decoction on spleen and stomach deficiency cold syndrome of chronic atrophic gastritis

作　　者：焦恩虎 王克鹏 李润东 JIAO Enhu;WANG Kepeng;LI Rundong(The Second Department of Pre-treatment,Zaozhuang Hospital of Traditional Chinese Medicine,Shandong Province,Zaozhuang277000,China;Department of Cardiovascular Disease,Zaozhuang Hospital of Traditional Chinese Medicine,Shandong Province,Zaozhuang277000,China;Department of Traditional Chinese Medicine,Zaozhuang Hospital of Traditional Chinese Medicine,Shandong Province,Zaozhuang277000,China)

机构地区：[1]山东省枣庄市中医医院治未病二科,山东枣庄277000 [2]山东省枣庄市中医医院心血管病科,山东枣庄277000 [3]山东省枣庄市中医医院中医内科,山东枣庄277000

出　　处：《中国当代医药》2023年第18期136-139,共4页China Modern Medicine

基　　金：第七批全国老中医药专家学术经验继承项目(国中医药人教函〔2022〕76号)。

摘　　要：目的观察新加汤合当归四逆汤加味治疗萎缩性胃炎脾胃虚寒证的效果。方法选取2022年5月至7月枣庄市中医医院收治的48例慢性萎缩性胃炎患者为研究对象,所有患者均属于脾胃虚寒证型,按照随机数字表法分为参照组(24例)与研究组(24例)。参照组采用香砂养胃丸中成药治疗,研究组采用新加汤合当归四逆汤加味治疗。比较两组的治疗效果、症状评分、不良反应、生活质量评分(SF-36)。结果研究组的症状改善情况优于参照组,总改善率高于参照组,差异有统计学意义(P<0.05)。治疗后两组的胃脘隐痛、畏寒肢冷、泛吐清水、精神疲倦的症状评分低于治疗前,且研究组低于参照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。两组患者治疗前的SF-36评分比较,差异无统计学意义(P>0.05);两组患者治疗后的SF-36评分高于治疗前,且研究组高于参照组,差异有统计学意义(P<0.05)。结论慢性萎缩性胃炎脾胃虚寒证患者接受中医经方加味治疗后能够辨证施治,有效改善患者胃黏膜收缩、胃部受损及肠化问题,能够降低患者症状评分,提升患者生活健康指数,并且用药安全有保障。Objective To observe the effect of Xinjia Decoction combined with Danggui Sini Decoction on patients with spleen and stomach deficiency cold syndrome of atrophic gastritis.Methods Forty-eight patients with chronic atrophic gastritis treated in Zaozhuang Hospital of Traditional Chinese Medicine from May to July 2022 were selected as the research subjects.All patients belonged to the syndrome type of spleen and stomach deficiency and cold,and were divided into the reference group(24 cases)and the research group(24 cases)according to random number table method.The control group was treated with Xiangsha Yangwei Pills,and the study group was treated with Xinjia Decoction combined with Danggui Sini Decoction.Treatment effects,symptom scores,adverse reactions,and quality of life scores(SF-36)were compared between the two groups.Results The symptom improvement of the study group was better than that of the reference group,and the total improvement rate was higher than that of the reference group,the difference was statistically significant(P<0.05).After treatment,the symptom scores of epigastric dull pain,chills,cold limbs,water vomiting and mental fatigue in the two groups were lower than before treatment,and the study group were lower than the reference group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).There was no significant difference in SF-36 scores between the two groups before treatment(P>0.05).The SF-36 score of the two groups after treatment was higher than that before treatment,and the study group was higher than the reference group,the differences were statistically significant(P<0.05).Conclusion Patients with spleen and stomach deficiency cold syndrome of chronic atrophic gastritis can be treated with syndrome differentiation after receiving traditional Chinese medicine prescription and flavor treatment,which can effectively improve the gastric mucosa contraction,stomach damage and intestinal

关 键 词：中医经方加味治疗 慢性萎缩性胃炎 脾胃虚寒证 症状评分 

分 类 号：R256.3[医药卫生—中医内科学]