SARS-CoV-2与Omicron变异株感染者血常规和生化指标的比较  

Comparison of blood routine and biochemical indicators between patients infected with SARSCoV-2 and Omicron variants

作　　者：黄海勇 梁雪雁 车玉传 范向平[1] 李茂城 焦美玲 吴显劲 HUANG Hai-yong;LIANG Xue-yan;CHE Yu-chuan;FAN Xiang-ping;LI Mao-cheng;JIAO Mei-ling;WU Xian-jing(Department of Clinical Laboratory,Huizhou Municipal Central Hospital,Huizhou 516001,China)

机构地区：[1]惠州市中心人民医院检验科,广东惠州516001

出　　处：《广东医科大学学报》2023年第3期287-290,共4页Journal of Guangdong Medical University

基　　金：惠州市科学技术局科研攻关项目(2021WC010311)。

摘　　要：目的分析新型冠状病毒SARS-CoV-2与Omicron变异株感染者血常规及生化指标的差异。方法收集44例SARS-CoV-2感染者(SARS-CoV-2组)以及49例Omicron变异株感染者(Omicron组)的临床资料,比较两组患者的首次血常规及生化指标结果。结果Omicron组患者的白细胞计数、中性粒细胞计数、中性粒细胞百分比、钾离子、钠离子、氯离子、尿素、总蛋白和白蛋白水平均高于SARS-CoV-2组(P<0.05或0.01),而淋巴细胞百分比、球蛋白水平以及钾离子、钠离子的异常率低于SARS-CoV-2感染组(P<0.05)。两组患者的淋巴细胞计数、尿素、肌酐、总胆红素等比较差异无统计学意义(P>0.05)。结论Omicron感染者早期炎症和部分生化指标变化较SARS-CoV-2患者差异显著。Objective To analyze the differences in blood routine and biochemical indicators between patients infected with SARS-CoV-2 and Omicron variants.Methods The clinical data of 44 patients infected with SARS-CoV-2(SARS-CoV-2 Group)and 49 patients infected with Omicron variants(Omicron Group)were collected,and the results of their first blood routine and biochemical indicators were compared between the two groups.Results The white blood cell count,neutrophil count,neutrophil percentage,potassium ion,sodium ion,chloride ion,urea,total protein and albumin levels of the Omicron Group were all higher than those of the SARS-CoV-2 Group(P<0.05 or 0.01),while the lymphocyte percentage,globulin level and abnormal rates of potassium ion and sodium ion of the Omicron Group were all lower than those of the SARS-CoV-2 Group(P<0.05).There were no statistical differences in the lymphocyte count,urea,creatinine,uric acid,and total bilirubin of the two groups(P>0.05).Conclusion The early inflammation and biochemical indicators of patients infected with Omicron variants change more significantly than the patients infected with SARS-CoV-2 patients.

关 键 词：新型冠状病毒肺炎 SARS-CoV-2 Omicron 血常规 生化指标 

分 类 号：R563.1[医药卫生—呼吸系统]